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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, Xie X, Jin Z, Peng J, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK, Xu Y, Yang H, Liu H. Dai W, et al. Among authors: jiang xm, jiang h. Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22. Science. 2020. PMID: 32321856 Free PMC article.
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Protein Cell. 2020 Oct;11(10):723-739. doi: 10.1007/s13238-020-00768-w. Epub 2020 Aug 4. Protein Cell. 2020. PMID: 32754890 Free PMC article.
Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Protein Cell. 2021 Jan;12(1):76-80. doi: 10.1007/s13238-020-00792-w. Protein Cell. 2021. PMID: 33029721 Free PMC article. No abstract available.
Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillette D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Protein Cell. 2022 Oct;13(10):778. doi: 10.1007/s13238-020-00801-y. Protein Cell. 2022. PMID: 33165830 Free PMC article. No abstract available.
Clinical effect and antiviral mechanism of T-705 in treating severe fever with thrombocytopenia syndrome.
Li H, Jiang XM, Cui N, Yuan C, Zhang SF, Lu QB, Yang ZD, Xin QL, Song YB, Zhang XA, Liu HZ, Du J, Fan XJ, Yuan L, Yuan YM, Wang Z, Wang J, Zhang L, Zhang DN, Wang ZB, Dai K, Bai JY, Hao ZN, Fan H, Fang LQ, Xiao G, Yang Y, Peng K, Wang HQ, Li JX, Zhang LK, Liu W. Li H, et al. Among authors: jiang xm. Signal Transduct Target Ther. 2021 Apr 16;6(1):145. doi: 10.1038/s41392-021-00541-3. Signal Transduct Target Ther. 2021. PMID: 33859168 Free PMC article. Clinical Trial.
349 results