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Effector function does not contribute to protection from virus challenge by a highly potent HIV broadly neutralizing antibody in nonhuman primates.
Hangartner L, Beauparlant D, Rakasz E, Nedellec R, Hozé N, McKenney K, Martins MA, Seabright GE, Allen JD, Weiler AM, Friedrich TC, Regoes RR, Crispin M, Burton DR. Hangartner L, et al. Sci Transl Med. 2021 Mar 17;13(585):eabe3349. doi: 10.1126/scitranslmed.abe3349. Sci Transl Med. 2021. PMID: 33731434 Free PMC article.
Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome.
Martins MA, Gonzalez-Nieto L, Ricciardi MJ, Bailey VK, Dang CM, Bischof GF, Pedreño-Lopez N, Pauthner MG, Burton DR, Parks CL, Earl P, Moss B, Rakasz EG, Lifson JD, Desrosiers RC, Watkins DI. Martins MA, et al. J Virol. 2020 Nov 23;94(24):e00979-20. doi: 10.1128/JVI.00979-20. Print 2020 Nov 23. J Virol. 2020. PMID: 33028714 Free PMC article.
Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies.
Pedreño-Lopez N, Dang CM, Rosen BC, Ricciardi MJ, Bailey VK, Gutman MJ, Gonzalez-Nieto L, Pauthner MG, Le K, Song G, Andrabi R, Weisgrau KL, Pomplun N, Martinez-Navio JM, Fuchs SP, Wrammert J, Rakasz EG, Lifson JD, Martins MA, Burton DR, Watkins DI, Magnani DM. Pedreño-Lopez N, et al. Mol Ther Methods Clin Dev. 2020 Feb 13;16:225-237. doi: 10.1016/j.omtm.2020.01.010. eCollection 2020 Mar 13. Mol Ther Methods Clin Dev. 2020. PMID: 32083148 Free PMC article.
Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
Gonzalez-Nieto L, Castro IM, Bischof GF, Shin YC, Ricciardi MJ, Bailey VK, Dang CM, Pedreño-Lopez N, Magnani DM, Ejima K, Allison DB, Gil HM, Evans DT, Rakasz EG, Lifson JD, Desrosiers RC, Martins MA. Gonzalez-Nieto L, et al. PLoS Pathog. 2019 Sep 30;15(9):e1008015. doi: 10.1371/journal.ppat.1008015. eCollection 2019 Sep. PLoS Pathog. 2019. PMID: 31568531 Free PMC article.
Vaccine protection against SIVmac239 acquisition.
Martins MA, Bischof GF, Shin YC, Lauer WA, Gonzalez-Nieto L, Watkins DI, Rakasz EG, Lifson JD, Desrosiers RC. Martins MA, et al. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1739-1744. doi: 10.1073/pnas.1814584116. Epub 2019 Jan 14. Proc Natl Acad Sci U S A. 2019. PMID: 30642966 Free PMC article.
The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques.
Martins MA, Gonzalez-Nieto L, Shin YC, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Pedreño-Lopez N, Bailey VK, Altman JD, Parks CL, Allison DB, Ejima K, Rakasz EG, Capuano S 3rd, Desrosiers RC, Lifson JD, Watkins DI. Martins MA, et al. J Virol. 2019 Feb 19;93(5):e01626-18. doi: 10.1128/JVI.01626-18. Print 2019 Mar 1. J Virol. 2019. PMID: 30541854 Free PMC article.
Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication.
Martins MA, Tully DC, Pedreño-Lopez N, von Bredow B, Pauthner MG, Shin YC, Yuan M, Lima NS, Bean DJ, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Bailey VK, Altman JD, Burton DR, Ejima K, Allison DB, Evans DT, Rakasz EG, Parks CL, Bonaldo MC, Capuano S 3rd, Lifson JD, Desrosiers RC, Allen TM, Watkins DI. Martins MA, et al. J Virol. 2018 Jul 31;92(16):e00690-18. doi: 10.1128/JVI.00690-18. Print 2018 Aug 15. J Virol. 2018. PMID: 29875239 Free PMC article.
19 results