Kjalke M - Search Results

1

Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake.

Bloem E, van den Biggelaar M, Wroblewska A, Voorberg J, Faber JH, Kjalke M, Stennicke HR, Mertens K, Meijer AB. Bloem E, et al. Among authors: kjalke m. J Biol Chem. 2013 Oct 11;288(41):29670-9. doi: 10.1074/jbc.M113.473116. Epub 2013 Sep 5. J Biol Chem. 2013. PMID: 24009077 Free PMC article.

2

Coagulation factor XIII variants with altered thrombin activation rates.

Andersen MD, Kjalke M, Bang S, Lautrup-Larsen I, Becker P, Andersen AS, Olsen OH, Stennicke HR. Andersen MD, et al. Among authors: kjalke m. Biol Chem. 2009 Dec;390(12):1279-83. doi: 10.1515/BC.2009.142. Biol Chem. 2009. PMID: 19804366

3

A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.

Stennicke HR, Kjalke M, Karpf DM, Balling KW, Johansen PB, Elm T, Øvlisen K, Möller F, Holmberg HL, Gudme CN, Persson E, Hilden I, Pelzer H, Rahbek-Nielsen H, Jespersgaard C, Bogsnes A, Pedersen AA, Kristensen AK, Peschke B, Kappers W, Rode F, Thim L, Tranholm M, Ezban M, Olsen EH, Bjørn SE. Stennicke HR, et al. Among authors: kjalke m. Blood. 2013 Mar 14;121(11):2108-16. doi: 10.1182/blood-2012-01-407494. Epub 2013 Jan 18. Blood. 2013. PMID: 23335368 Free PMC article.

4

Factor VIII with a 237 amino acid B-domain has an extended half-life in F8-knockout mice.

Bloem E, Karpf DM, Nørby PL, Johansen PB, Loftager M, Rahbek-Nielsen H, Petersen HH, Blouse GE, Thim L, Kjalke M, Bolt G. Bloem E, et al. Among authors: kjalke m. J Thromb Haemost. 2019 Feb;17(2):350-360. doi: 10.1111/jth.14355. Epub 2019 Jan 25. J Thromb Haemost. 2019. PMID: 30525289 Free article.

5

A novel next-generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys.

Lauritzen B, Bjelke M, Björkdahl O, Bloem E, Keane K, Kjalke M, Rossen M, Lippert SL, Weldingh KN, Skydsgaard M, Kjellev S. Lauritzen B, et al. Among authors: kjalke m. J Thromb Haemost. 2022 Jun;20(6):1312-1324. doi: 10.1111/jth.15682. Epub 2022 Mar 6. J Thromb Haemost. 2022. PMID: 35191180 Free PMC article.

6

Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins.

Ploug M, Kjalke M, Rønne E, Weidle U, Høyer-Hansen G, Danø K. Ploug M, et al. Among authors: kjalke m. J Biol Chem. 1993 Aug 15;268(23):17539-46. J Biol Chem. 1993. PMID: 8394346 Free article.

7

Incorporation of an active site inhibitor in factor VIIa alters the affinity for tissue factor.

Sorensen BB, Persson E, Freskgârd PO, Kjalke M, Ezban M, Williams T, Rao LV. Sorensen BB, et al. Among authors: kjalke m. J Biol Chem. 1997 May 2;272(18):11863-8. doi: 10.1074/jbc.272.18.11863. J Biol Chem. 1997. PMID: 9115245 Free article.

8

High-affinity von Willebrand factor binding does not affect the anatomical or hepatocellular distribution of factor VIII in rats.

Øie CI, Roepstorff K, Behrens C, Bøggild Kristensen J, Karpf DM, Bolt G, Gudme CN, Kjalke M, Smedsrød B, Appa RS. Øie CI, et al. Among authors: kjalke m. J Thromb Haemost. 2016 Sep;14(9):1803-13. doi: 10.1111/jth.13406. Epub 2016 Aug 24. J Thromb Haemost. 2016. PMID: 27378673 Free article.

9

Purification and characterization of a new recombinant factor VIII (N8).

Thim L, Vandahl B, Karlsson J, Klausen NK, Pedersen J, Krogh TN, Kjalke M, Petersen JM, Johnsen LB, Bolt G, Nørby PL, Steenstrup TD. Thim L, et al. Among authors: kjalke m. Haemophilia. 2010 Mar;16(2):349-59. doi: 10.1111/j.1365-2516.2009.02135.x. Epub 2009 Nov 11. Haemophilia. 2010. PMID: 19906157

10

An overview of turoctocog alfa pegol (N8-GP; ESPEROCT^® ) assay performance: Implications for postadministration monitoring.

Ezban M, Hansen M, Kjalke M. Ezban M, et al. Among authors: kjalke m. Haemophilia. 2020 Jan;26(1):156-163. doi: 10.1111/hae.13897. Epub 2019 Dec 6. Haemophilia. 2020. PMID: 31809565 Free PMC article. Review.

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