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Lipid nanoparticles for mRNA delivery.
Hou X, Zaks T, Langer R, Dong Y. Hou X, et al. Among authors: langer r. Nat Rev Mater. 2021;6(12):1078-1094. doi: 10.1038/s41578-021-00358-0. Epub 2021 Aug 10. Nat Rev Mater. 2021. PMID: 34394960 Free PMC article. Review.
Drug delivery and targeting.
Langer R. Langer R. Nature. 1998 Apr 30;392(6679 Suppl):5-10. Nature. 1998. PMID: 9579855 Review.
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.
Akinc A, Zumbuehl A, Goldberg M, Leshchiner ES, Busini V, Hossain N, Bacallado SA, Nguyen DN, Fuller J, Alvarez R, Borodovsky A, Borland T, Constien R, de Fougerolles A, Dorkin JR, Narayanannair Jayaprakash K, Jayaraman M, John M, Koteliansky V, Manoharan M, Nechev L, Qin J, Racie T, Raitcheva D, Rajeev KG, Sah DW, Soutschek J, Toudjarska I, Vornlocher HP, Zimmermann TS, Langer R, Anderson DG. Akinc A, et al. Among authors: langer r. Nat Biotechnol. 2008 May;26(5):561-9. doi: 10.1038/nbt1402. Epub 2008 Apr 27. Nat Biotechnol. 2008. PMID: 18438401 Free PMC article.
Knocking down barriers: advances in siRNA delivery.
Whitehead KA, Langer R, Anderson DG. Whitehead KA, et al. Among authors: langer r. Nat Rev Drug Discov. 2009 Feb;8(2):129-38. doi: 10.1038/nrd2742. Nat Rev Drug Discov. 2009. PMID: 19180106 Free PMC article. Review.
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.
Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG. Lee H, et al. Among authors: langer r. Nat Nanotechnol. 2012 Jun 3;7(6):389-93. doi: 10.1038/nnano.2012.73. Nat Nanotechnol. 2012. PMID: 22659608 Free PMC article.
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling.
Sahay G, Querbes W, Alabi C, Eltoukhy A, Sarkar S, Zurenko C, Karagiannis E, Love K, Chen D, Zoncu R, Buganim Y, Schroeder A, Langer R, Anderson DG. Sahay G, et al. Among authors: langer r. Nat Biotechnol. 2013 Jul;31(7):653-8. doi: 10.1038/nbt.2614. Epub 2013 Jun 23. Nat Biotechnol. 2013. PMID: 23792629 Free PMC article.
2,233 results