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Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane.
Sabnis A, Hagart KL, Klöckner A, Becce M, Evans LE, Furniss RCD, Mavridou DA, Murphy R, Stevens MM, Davies JC, Larrouy-Maumus GJ, Clarke TB, Edwards AM. Sabnis A, et al. Among authors: larrouy maumus gj. Elife. 2021 Apr 6;10:e65836. doi: 10.7554/eLife.65836. Elife. 2021. PMID: 33821795 Free PMC article.
Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo.
Berger CN, Crepin VF, Roumeliotis TI, Wright JC, Carson D, Pevsner-Fischer M, Furniss RCD, Dougan G, Dori-Bachash M, Yu L, Clements A, Collins JW, Elinav E, Larrouy-Maumus GJ, Choudhary JS, Frankel G. Berger CN, et al. Among authors: larrouy maumus gj. Cell Metab. 2017 Nov 7;26(5):738-752.e6. doi: 10.1016/j.cmet.2017.09.003. Epub 2017 Oct 5. Cell Metab. 2017. PMID: 28988824 Free PMC article.
Rapid detection and discrimination of chromosome- and MCR-plasmid-mediated resistance to polymyxins by MALDI-TOF MS in Escherichia coli: the MALDIxin test.
Dortet L, Bonnin RA, Pennisi I, Gauthier L, Jousset AB, Dabos L, Furniss RCD, Mavridou DAI, Bogaerts P, Glupczynski Y, Potron A, Plesiat P, Beyrouthy R, Robin F, Bonnet R, Naas T, Filloux A, Larrouy-Maumus G. Dortet L, et al. J Antimicrob Chemother. 2018 Dec 1;73(12):3359-3367. doi: 10.1093/jac/dky330. J Antimicrob Chemother. 2018. PMID: 30184212
The clue is in the lipid A: Rapid detection of colistin resistance.
Furniss RCD, Kostrzewa M, Mavridou DAI, Larrouy-Maumus G. Furniss RCD, et al. PLoS Pathog. 2020 Apr 9;16(4):e1008331. doi: 10.1371/journal.ppat.1008331. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32271847 Free PMC article. No abstract available.
Breaking antimicrobial resistance by disrupting extracytoplasmic protein folding.
Furniss RCD, Kaderabkova N, Barker D, Bernal P, Maslova E, Antwi AAA, McNeil HE, Pugh HL, Dortet L, Blair JMA, Larrouy-Maumus G, McCarthy RR, Gonzalez D, Mavridou DAI. Furniss RCD, et al. Elife. 2022 Jan 13;11:e57974. doi: 10.7554/eLife.57974. Elife. 2022. PMID: 35025730 Free PMC article.
75 results