Lawrence D - Search Results

1

An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells.

Wilson NS, Yang B, Yang A, Loeser S, Marsters S, Lawrence D, Li Y, Pitti R, Totpal K, Yee S, Ross S, Vernes JM, Lu Y, Adams C, Offringa R, Kelley B, Hymowitz S, Daniel D, Meng G, Ashkenazi A. Wilson NS, et al. Among authors: lawrence d. Cancer Cell. 2011 Jan 18;19(1):101-13. doi: 10.1016/j.ccr.2010.11.012. Cancer Cell. 2011. PMID: 21251615 Free article.

2

Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts.

Daniel D, Yang B, Lawrence DA, Totpal K, Balter I, Lee WP, Gogineni A, Cole MJ, Yee SF, Ross S, Ashkenazi A. Daniel D, et al. Among authors: lawrence da. Blood. 2007 Dec 1;110(12):4037-46. doi: 10.1182/blood-2007-02-076075. Epub 2007 Aug 27. Blood. 2007. PMID: 17724141 Free article.

3

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling.

Jin Z, Li Y, Pitti R, Lawrence D, Pham VC, Lill JR, Ashkenazi A. Jin Z, et al. Among authors: lawrence d. Cell. 2009 May 15;137(4):721-35. doi: 10.1016/j.cell.2009.03.015. Epub 2009 May 7. Cell. 2009. PMID: 19427028 Free article.

4

TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer.

Gonzalvez F, Lawrence D, Yang B, Yee S, Pitti R, Marsters S, Pham VC, Stephan JP, Lill J, Ashkenazi A. Gonzalvez F, et al. Among authors: lawrence d. Mol Cell. 2012 Dec 28;48(6):888-99. doi: 10.1016/j.molcel.2012.09.031. Epub 2012 Nov 8. Mol Cell. 2012. PMID: 23142077 Free article.

5

Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5.

Adams C, Totpal K, Lawrence D, Marsters S, Pitti R, Yee S, Ross S, Deforge L, Koeppen H, Sagolla M, Compaan D, Lowman H, Hymowitz S, Ashkenazi A. Adams C, et al. Among authors: lawrence d. Cell Death Differ. 2008 Apr;15(4):751-61. doi: 10.1038/sj.cdd.4402306. Epub 2008 Jan 25. Cell Death Differ. 2008. PMID: 18219321

6

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

Sharp DA, Lawrence DA, Ashkenazi A. Sharp DA, et al. J Biol Chem. 2005 May 13;280(19):19401-9. doi: 10.1074/jbc.M413962200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15760909 Free article.

7

Death-receptor activation halts clathrin-dependent endocytosis.

Austin CD, Lawrence DA, Peden AA, Varfolomeev EE, Totpal K, De Mazière AM, Klumperman J, Arnott D, Pham V, Scheller RH, Ashkenazi A. Austin CD, et al. Among authors: lawrence da. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10283-10288. doi: 10.1073/pnas.0604044103. Epub 2006 Jun 26. Proc Natl Acad Sci U S A. 2006. PMID: 16801533 Free PMC article.

8

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

Wagner KW, Punnoose EA, Januario T, Lawrence DA, Pitti RM, Lancaster K, Lee D, von Goetz M, Yee SF, Totpal K, Huw L, Katta V, Cavet G, Hymowitz SG, Amler L, Ashkenazi A. Wagner KW, et al. Among authors: lawrence da. Nat Med. 2007 Sep;13(9):1070-7. doi: 10.1038/nm1627. Epub 2007 Sep 2. Nat Med. 2007. PMID: 17767167

9

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.

Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. Lu M, et al. Among authors: lawrence da. Science. 2014 Jul 4;345(6192):98-101. doi: 10.1126/science.1254312. Science. 2014. PMID: 24994655 Free PMC article.

10

Membrane display and functional analysis of juxtacrine ligand-receptor signaling.

Nair PM, Ngu H, Torres E, Marsters S, Lawrence DA, Stephan JP, Komuves L, Ashkenazi A. Nair PM, et al. Biotechniques. 2015 Oct 1;59(4):231-8, 240. doi: 10.2144/000114342. eCollection 2015 Oct. Biotechniques. 2015. PMID: 26458551 Free article.

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