Lazzara M - Search Results

1

Decreased internalisation of erbB1 mutants in lung cancer is linked with a mechanism conferring sensitivity to gefitinib.

Hendriks BS, Griffiths GJ, Benson R, Kenyon D, Lazzara M, Swinton J, Beck S, Hickinson M, Beusmans JM, Lauffenburger D, de Graaf D. Hendriks BS, et al. Among authors: lazzara m. Syst Biol (Stevenage). 2006 Nov;153(6):457-66. doi: 10.1049/ip-syb:20050108. Syst Biol (Stevenage). 2006. PMID: 17186707

2

Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.

Lazzara MJ, Lane K, Chan R, Jasper PJ, Yaffe MB, Sorger PK, Jacks T, Neel BG, Lauffenburger DA. Lazzara MJ, et al. Cancer Res. 2010 May 1;70(9):3843-50. doi: 10.1158/0008-5472.CAN-09-3421. Epub 2010 Apr 20. Cancer Res. 2010. PMID: 20406974 Free PMC article.

3

Quantitative modeling perspectives on the ErbB system of cell regulatory processes.

Lazzara MJ, Lauffenburger DA. Lazzara MJ, et al. Exp Cell Res. 2009 Feb 15;315(4):717-25. doi: 10.1016/j.yexcr.2008.10.033. Epub 2008 Nov 5. Exp Cell Res. 2009. PMID: 19022246 Review.

4

Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors.

Ercan D, Xu C, Yanagita M, Monast CS, Pratilas CA, Montero J, Butaney M, Shimamura T, Sholl L, Ivanova EV, Tadi M, Rogers A, Repellin C, Capelletti M, Maertens O, Goetz EM, Letai A, Garraway LA, Lazzara MJ, Rosen N, Gray NS, Wong KK, Jänne PA. Ercan D, et al. Among authors: lazzara mj. Cancer Discov. 2012 Oct;2(10):934-47. doi: 10.1158/2159-8290.CD-12-0103. Epub 2012 Sep 7. Cancer Discov. 2012. PMID: 22961667 Free PMC article.

5

An engineering design approach to systems biology.

Janes KA, Chandran PL, Ford RM, Lazzara MJ, Papin JA, Peirce SM, Saucerman JJ, Lauffenburger DA. Janes KA, et al. Among authors: lazzara mj. Integr Biol (Camb). 2017 Jul 17;9(7):574-583. doi: 10.1039/c7ib00014f. Integr Biol (Camb). 2017. PMID: 28590470 Free PMC article. Review.

6

Diminished functional role and altered localization of SHP2 in non-small cell lung cancer cells with EGFR-activating mutations.

Furcht CM, Muñoz Rojas AR, Nihalani D, Lazzara MJ. Furcht CM, et al. Among authors: lazzara mj. Oncogene. 2013 May 2;32(18):2346-55, 2355.e1-10. doi: 10.1038/onc.2012.240. Epub 2012 Jul 9. Oncogene. 2013. PMID: 22777356 Free PMC article.

7

ERK1/2 blockade prevents epithelial-mesenchymal transition in lung cancer cells and promotes their sensitivity to EGFR inhibition.

Buonato JM, Lazzara MJ. Buonato JM, et al. Among authors: lazzara mj. Cancer Res. 2014 Jan 1;74(1):309-19. doi: 10.1158/0008-5472.CAN-12-4721. Epub 2013 Oct 9. Cancer Res. 2014. PMID: 24108744 Free PMC article.

8

Differential parsing of EGFR endocytic flux among parallel internalization pathways in lung cancer cells with EGFR-activating mutations.

Walsh AM, Lazzara MJ. Walsh AM, et al. Among authors: lazzara mj. Integr Biol (Camb). 2014 Mar;6(3):312-23. doi: 10.1039/c3ib40176f. Epub 2014 Jan 21. Integr Biol (Camb). 2014. PMID: 24445374

9

Multivariate signaling regulation by SHP2 differentially controls proliferation and therapeutic response in glioma cells.

Furcht CM, Buonato JM, Skuli N, Mathew LK, Muñoz Rojas AR, Simon MC, Lazzara MJ. Furcht CM, et al. Among authors: lazzara mj. J Cell Sci. 2014 Aug 15;127(Pt 16):3555-67. doi: 10.1242/jcs.150862. Epub 2014 Jun 20. J Cell Sci. 2014. PMID: 24951116 Free PMC article.

10

Breast Cancer Antiestrogen Resistance 3 (BCAR3) promotes tumor growth and progression in triple-negative breast cancer.

Arras J, Thomas KS, Myers PJ, Cross AM, Osei AD, Vazquez GE, Atkins KA, Conaway MR, Jones MK, Lazzara MJ, Bouton AH. Arras J, et al. Among authors: lazzara mj. Am J Cancer Res. 2021 Oct 15;11(10):4768-4787. eCollection 2021. Am J Cancer Res. 2021. PMID: 34765292 Free PMC article.

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