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PPARdelta is a very low-density lipoprotein sensor in macrophages.
Chawla A, Lee CH, Barak Y, He W, Rosenfeld J, Liao D, Han J, Kang H, Evans RM. Chawla A, et al. Among authors: lee ch. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1268-73. doi: 10.1073/pnas.0337331100. Epub 2003 Jan 22. Proc Natl Acad Sci U S A. 2003. PMID: 12540828 Free PMC article.
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Sonoda J, et al. Among authors: lee ch. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2198-203. doi: 10.1073/pnas.0409481102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671183 Free PMC article.
PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. Barish GD, et al. Among authors: lee ch. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4271-6. doi: 10.1073/pnas.0711875105. Epub 2008 Mar 12. Proc Natl Acad Sci U S A. 2008. PMID: 18337509 Free PMC article.
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis.
Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, Lee CH, Evans RM. Nofsinger RR, et al. Among authors: lee ch. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):20021-6. doi: 10.1073/pnas.0811012105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066220 Free PMC article.
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