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High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models.
Li W, Schäfer A, Kulkarni SS, Liu X, Martinez DR, Chen C, Sun Z, Leist SR, Drelich A, Zhang L, Ura ML, Berezuk A, Chittori S, Leopold K, Mannar D, Srivastava SS, Zhu X, Peterson EC, Tseng CT, Mellors JW, Falzarano D, Subramaniam S, Baric RS, Dimitrov DS. Li W, et al. Among authors: leopold k. Cell. 2020 Oct 15;183(2):429-441.e16. doi: 10.1016/j.cell.2020.09.007. Epub 2020 Sep 4. Cell. 2020. PMID: 32941803 Free PMC article.
Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Zhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S. Zhu X, et al. Among authors: leopold k. PLoS Biol. 2021 Apr 29;19(4):e3001237. doi: 10.1371/journal.pbio.3001237. eCollection 2021 Apr. PLoS Biol. 2021. PMID: 33914735 Free PMC article.
Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation.
Fraser BJ, Beldar S, Seitova A, Hutchinson A, Mannar D, Li Y, Kwon D, Tan R, Wilson RP, Leopold K, Subramaniam S, Halabelian L, Arrowsmith CH, Bénard F. Fraser BJ, et al. Among authors: leopold k. Nat Chem Biol. 2022 Sep;18(9):963-971. doi: 10.1038/s41589-022-01059-7. Epub 2022 Jun 8. Nat Chem Biol. 2022. PMID: 35676539
Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold.
Castells-Graells R, Meador K, Arbing MA, Sawaya MR, Gee M, Cascio D, Gleave E, Debreczeni JÉ, Breed J, Leopold K, Patel A, Jahagirdar D, Lyons B, Subramaniam S, Phillips C, Yeates TO. Castells-Graells R, et al. Among authors: leopold k. Proc Natl Acad Sci U S A. 2023 Sep 12;120(37):e2305494120. doi: 10.1073/pnas.2305494120. Epub 2023 Sep 5. Proc Natl Acad Sci U S A. 2023. PMID: 37669364 Free PMC article.
soulspace: Integrated youth mental health care in Berlin, Germany-An introduction to the program and a description of its users.
Bechdolf A, Hanser S, Baumgardt J, Brose A, Jäckel D, Döring S, Holzner L, Aliakbari N, von Hardenberg L, Shmuilovich O, Gencaggi D, Schellong M, Izat Y, Leopold S, Ituarte BP, Leopold K. Bechdolf A, et al. Among authors: leopold k. Early Interv Psychiatry. 2024 Mar 14. doi: 10.1111/eip.13522. Online ahead of print. Early Interv Psychiatry. 2024. PMID: 38486399
237 results