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Immune signatures underlying post-acute COVID-19 lung sequelae.
Cheon IS, Li C, Son YM, Goplen NP, Wu Y, Cassmann T, Wang Z, Wei X, Tang J, Li Y, Marlow H, Hughes S, Hammel L, Cox TM, Goddery E, Ayasoufi K, Weiskopf D, Boonyaratanakornkit J, Dong H, Li H, Chakraborty R, Johnson AJ, Edell E, Taylor JJ, Kaplan MH, Sette A, Bartholmai BJ, Kern R, Vassallo R, Sun J. Cheon IS, et al. Among authors: li c, li y, li h. Sci Immunol. 2021 Nov 12;6(65):eabk1741. doi: 10.1126/sciimmunol.abk1741. Epub 2021 Nov 12. Sci Immunol. 2021. PMID: 34591653 Free PMC article. Clinical Trial.
NKG7 Is a T-cell-Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy.
Wen T, Barham W, Li Y, Zhang H, Gicobi JK, Hirdler JB, Liu X, Ham H, Peterson Martinez KE, Lucien F, Lavoie RR, Li H, Correia C, Monie DD, An Z, Harrington SM, Wu X, Guo R, Dronca RS, Mansfield AS, Yan Y, Markovic SN, Park SS, Sun J, Qin H, Liu MC, Vasmatzis G, Billadeau DD, Dong H. Wen T, et al. Among authors: li y, li h. Cancer Immunol Res. 2022 Feb;10(2):162-181. doi: 10.1158/2326-6066.CIR-21-0539. Epub 2021 Dec 15. Cancer Immunol Res. 2022. PMID: 34911739 Free PMC article.
Senescent alveolar macrophages promote early-stage lung tumorigenesis.
Prieto LI, Sturmlechner I, Graves SI, Zhang C, Goplen NP, Yi ES, Sun J, Li H, Baker DJ. Prieto LI, et al. Among authors: li h. Cancer Cell. 2023 Jul 10;41(7):1261-1275.e6. doi: 10.1016/j.ccell.2023.05.006. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267954
Vertical Transmission of SARS-CoV-2-Specific Antibodies and Cytokine Profiles in Pregnancy.
Monroe JM, Quach HQ, Punia S, Enninga EAL, Fedyshyn Y, Girsch JH, Fedyshyn B, Lemens M, Littlefield D, Behl S, Sintim-Aboagye E, Mejia Plazas MC, Yamaoka S, Ebihara H, Pandey A, Correia C, Ung CY, Li H, Vassallo R, Sun J, Johnson EL, Olson JE, Theel ES, Badley AD, Kennedy RB, Theiler RN, Chakraborty R. Monroe JM, et al. Among authors: li h. J Infect Dis. 2024 Feb 14;229(2):473-484. doi: 10.1093/infdis/jiad399. J Infect Dis. 2024. PMID: 37786979
Maternal SARS-CoV-2 infection in pregnancy disrupts gene expression in Hofbauer cells with limited impact on cytotrophoblasts.
Enninga EAL, Quach HQ, Jang JS, de Araujo Correia MCM, Fedyshyn Y, Fedyshyn B, Lemens M, Littlefield D, Behl S, Sintim-Aboagye E, Mejia Plazas MC, Cardenas MC, Chakraborty S, Yamaoka S, Ebihara H, Pandey A, Li H, Badley AD, Johnson EL, Sun J, Norgan AP, Theiler RN, Chakraborty R. Enninga EAL, et al. Among authors: li h. PLoS Pathog. 2024 Feb 7;20(2):e1011990. doi: 10.1371/journal.ppat.1011990. eCollection 2024 Feb. PLoS Pathog. 2024. PMID: 38324589 Free PMC article.
PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy.
Tu X, Qin B, Zhang Y, Zhang C, Kahila M, Nowsheen S, Yin P, Yuan J, Pei H, Li H, Yu J, Song Z, Zhou Q, Zhao F, Liu J, Zhang C, Dong H, Mutter RW, Lou Z. Tu X, et al. Among authors: li h. Mol Cell. 2019 Jun 20;74(6):1215-1226.e4. doi: 10.1016/j.molcel.2019.04.005. Epub 2019 Apr 30. Mol Cell. 2019. PMID: 31053471 Free PMC article.
p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. Sturmlechner I, et al. Among authors: li h. Science. 2021 Oct 29;374(6567):eabb3420. doi: 10.1126/science.abb3420. Epub 2021 Oct 29. Science. 2021. PMID: 34709885 Free PMC article.
Generation of chromosome 1p/19q co-deletion by CRISPR/Cas9-guided genomic editing.
Li C, Liu Z, Zhang X, Wang H, Friedman GK, Ding Q, Zhao X, Li H, Kim K, Yu X, Burt Nabors L, Han X, Zhao R. Li C, et al. Among authors: li h. Neurooncol Adv. 2022 Aug 18;4(1):vdac131. doi: 10.1093/noajnl/vdac131. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 36225650 Free PMC article.
Glucocorticoids unmask silent non-coding genetic risk variants for common diseases.
Nguyen TTL, Gao H, Liu D, Philips TJ, Ye Z, Lee JH, Shi GX, Copenhaver K, Zhang L, Wei L, Yu J, Zhang H, Barath A, Luong M, Zhang C, Gaspar-Maia A, Li H, Wang L, Ordog T, Weinshilboum RM. Nguyen TTL, et al. Among authors: li h. Nucleic Acids Res. 2022 Nov 11;50(20):11635-11653. doi: 10.1093/nar/gkac1045. Nucleic Acids Res. 2022. PMID: 36399508 Free PMC article.
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