Liberman JA - Search Results

1

T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site.

James EA, van Haren SD, Ettinger RA, Fijnvandraat K, Liberman JA, Kwok WW, Voorberg J, Pratt KP. James EA, et al. Among authors: liberman ja. J Thromb Haemost. 2011 Apr;9(4):689-99. doi: 10.1111/j.1538-7836.2011.04202.x. J Thromb Haemost. 2011. PMID: 21251204 Free PMC article.

2

FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity.

Ettinger RA, Liberman JA, Gunasekera D, Puranik K, James EA, Thompson AR, Pratt KP. Ettinger RA, et al. Among authors: liberman ja. Blood Adv. 2018 Feb 27;2(4):309-322. doi: 10.1182/bloodadvances.2017013482. Blood Adv. 2018. PMID: 29444872 Free PMC article.

3

Molecular mechanism for preQ1-II riboswitch function revealed by molecular dynamics.

Aytenfisu AH, Liberman JA, Wedekind JE, Mathews DH. Aytenfisu AH, et al. Among authors: liberman ja. RNA. 2015 Nov;21(11):1898-907. doi: 10.1261/rna.051367.115. Epub 2015 Sep 14. RNA. 2015. PMID: 26370581 Free PMC article.

4

Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics.

Liberman JA, Suddala KC, Aytenfisu A, Chan D, Belashov IA, Salim M, Mathews DH, Spitale RC, Walter NG, Wedekind JE. Liberman JA, et al. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3485-94. doi: 10.1073/pnas.1503955112. Epub 2015 Jun 23. Proc Natl Acad Sci U S A. 2015. PMID: 26106162 Free PMC article.

5

ITC analysis of ligand binding to preQ₁ riboswitches.

Liberman JA, Bogue JT, Jenkins JL, Salim M, Wedekind JE. Liberman JA, et al. Methods Enzymol. 2014;549:435-50. doi: 10.1016/B978-0-12-801122-5.00018-0. Methods Enzymol. 2014. PMID: 25432759 Free PMC article.

6

Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure.

Suddala KC, Rinaldi AJ, Feng J, Mustoe AM, Eichhorn CD, Liberman JA, Wedekind JE, Al-Hashimi HM, Brooks CL 3rd, Walter NG. Suddala KC, et al. Among authors: liberman ja. Nucleic Acids Res. 2013 Dec;41(22):10462-75. doi: 10.1093/nar/gkt798. Epub 2013 Sep 3. Nucleic Acids Res. 2013. PMID: 24003028 Free PMC article.

7

Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold.

Liberman JA, Salim M, Krucinska J, Wedekind JE. Liberman JA, et al. Nat Chem Biol. 2013 Jun;9(6):353-5. doi: 10.1038/nchembio.1231. Epub 2013 Apr 14. Nat Chem Biol. 2013. PMID: 23584677 Free PMC article.

8

A transition-state interaction shifts nucleobase ionization toward neutrality to facilitate small ribozyme catalysis.

Liberman JA, Guo M, Jenkins JL, Krucinska J, Chen Y, Carey PR, Wedekind JE. Liberman JA, et al. J Am Chem Soc. 2012 Oct 17;134(41):16933-6. doi: 10.1021/ja3070528. Epub 2012 Oct 3. J Am Chem Soc. 2012. PMID: 22989273 Free PMC article.

9

Crystallographic analysis of small ribozymes and riboswitches.

Lippa GM, Liberman JA, Jenkins JL, Krucinska J, Salim M, Wedekind JE. Lippa GM, et al. Among authors: liberman ja. Methods Mol Biol. 2012;848:159-84. doi: 10.1007/978-1-61779-545-9_11. Methods Mol Biol. 2012. PMID: 22315069 Free PMC article.

10

Riboswitch structure in the ligand-free state.

Liberman JA, Wedekind JE. Liberman JA, et al. Wiley Interdiscip Rev RNA. 2012 May-Jun;3(3):369-84. doi: 10.1002/wrna.114. Epub 2011 Sep 28. Wiley Interdiscip Rev RNA. 2012. PMID: 21957061 Free PMC article. Review.

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