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Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.
Okoye AA, Hansen SG, Vaidya M, Fukazawa Y, Park H, Duell DM, Lum R, Hughes CM, Ventura AB, Ainslie E, Ford JC, Morrow D, Gilbride RM, Legasse AW, Hesselgesser J, Geleziunas R, Li Y, Oswald K, Shoemaker R, Fast R, Bosche WJ, Borate BR, Edlefsen PT, Axthelm MK, Picker LJ, Lifson JD. Okoye AA, et al. Among authors: lifson jd. Nat Med. 2018 Sep;24(9):1430-1440. doi: 10.1038/s41591-018-0130-7. Epub 2018 Aug 6. Nat Med. 2018. PMID: 30082858 Free PMC article.
Protection of Macaca nemestrina from disease following pathogenic simian immunodeficiency virus (SIV) challenge: utilization of SIV nucleocapsid mutant DNA vaccines with and without an SIV protein boost.
Gorelick RJ, Benveniste RE, Lifson JD, Yovandich JL, Morton WR, Kuller L, Flynn BM, Fisher BA, Rossio JL, Piatak M Jr, Bess JW Jr, Henderson LE, Arthur LO. Gorelick RJ, et al. Among authors: lifson jd. J Virol. 2000 Dec;74(24):11935-49. doi: 10.1128/jvi.74.24.11935-11949.2000. J Virol. 2000. PMID: 11090194 Free PMC article.
Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment.
Lifson JD, Rossio JL, Piatak M Jr, Parks T, Li L, Kiser R, Coalter V, Fisher B, Flynn BM, Czajak S, Hirsch VM, Reimann KA, Schmitz JE, Ghrayeb J, Bischofberger N, Nowak MA, Desrosiers RC, Wodarz D. Lifson JD, et al. J Virol. 2001 Nov;75(21):10187-99. doi: 10.1128/JVI.75.21.10187-10199.2001. J Virol. 2001. PMID: 11581387 Free PMC article.
Transient early post-inoculation anti-retroviral treatment facilitates controlled infection with sparing of CD4+ T cells in gut-associated lymphoid tissues in SIVmac239-infected rhesus macaques, but not resistance to rechallenge.
Lifson JD, Piatak M Jr, Cline AN, Rossio JL, Purcell J, Pandrea I, Bischofberger N, Blanchard J, Veazey RS. Lifson JD, et al. J Med Primatol. 2003 Aug;32(4-5):201-10. doi: 10.1034/j.1600-0684.2003.00026.x. J Med Primatol. 2003. PMID: 14498980
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Friedrich TC, Dodds EJ, Yant LJ, Vojnov L, Rudersdorf R, Cullen C, Evans DT, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Hughes AL, Wilson N, O'Connor DH, Watkins DI. Friedrich TC, et al. Nat Med. 2004 Mar;10(3):275-81. doi: 10.1038/nm998. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966520
Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.
Picker LJ, Hagen SI, Lum R, Reed-Inderbitzin EF, Daly LM, Sylwester AW, Walker JM, Siess DC, Piatak M Jr, Wang C, Allison DB, Maino VC, Lifson JD, Kodama T, Axthelm MK. Picker LJ, et al. Among authors: lifson jd. J Exp Med. 2004 Nov 15;200(10):1299-314. doi: 10.1084/jem.20041049. J Exp Med. 2004. PMID: 15545355 Free PMC article.
470 results