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CTLA-4 can function as a negative regulator of T cell activation.
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA. Walunas TL, et al. Among authors: linsley ps. Immunity. 1994 Aug;1(5):405-13. doi: 10.1016/1074-7613(94)90071-x. Immunity. 1994. PMID: 7882171
Role of the CD28 receptor in T-cell activation.
June CH, Ledbetter JA, Linsley PS, Thompson CB. June CH, et al. Among authors: linsley ps. Immunol Today. 1990 Jun;11(6):211-6. doi: 10.1016/0167-5699(90)90085-n. Immunol Today. 1990. PMID: 2162180 Free article. Review.
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms.
Parry RV, Chemnitz JM, Frauwirth KA, Lanfranco AR, Braunstein I, Kobayashi SV, Linsley PS, Thompson CB, Riley JL. Parry RV, et al. Among authors: linsley ps. Mol Cell Biol. 2005 Nov;25(21):9543-53. doi: 10.1128/MCB.25.21.9543-9553.2005. Mol Cell Biol. 2005. PMID: 16227604 Free PMC article.
305 results