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Placebo-Controlled Trials of Covid-19 Vaccines - Why We Still Need Them.
WHO Ad Hoc Expert Group on the Next Steps for Covid-19 Vaccine Evaluation; Krause PR, Fleming TR, Longini IM, Peto R, Beral V, Bhargava B, Cravioto A, Cramer JP, Ellenberg SS, Figueroa JP, Halloran E, Henao-Restrepo AM, Ryan MJ, Levine MM, Nason M, Nohynek HM, Plotkin S, Rees H, Singh JA, Swaminathan S. WHO Ad Hoc Expert Group on the Next Steps for Covid-19 Vaccine Evaluation, et al. Among authors: longini im. N Engl J Med. 2021 Jan 14;384(2):e2. doi: 10.1056/NEJMp2033538. Epub 2020 Dec 2. N Engl J Med. 2021. PMID: 33264543 No abstract available.
Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial.
Henao-Restrepo AM, Longini IM, Egger M, Dean NE, Edmunds WJ, Camacho A, Carroll MW, Doumbia M, Draguez B, Duraffour S, Enwere G, Grais R, Gunther S, Hossmann S, Kondé MK, Kone S, Kuisma E, Levine MM, Mandal S, Norheim G, Riveros X, Soumah A, Trelle S, Vicari AS, Watson CH, Kéïta S, Kieny MP, Røttingen JA. Henao-Restrepo AM, et al. Among authors: longini im. Lancet. 2015 Aug 29;386(9996):857-66. doi: 10.1016/S0140-6736(15)61117-5. Epub 2015 Aug 3. Lancet. 2015. PMID: 26248676 Clinical Trial.
Ebola vaccination - Authors' reply.
Longini IM, Egger M, Dean NE, Edmunds WJ, Henao-Restrepo AM; study steering group. Longini IM, et al. Lancet. 2015 Dec 19;386(10012):2480. doi: 10.1016/S0140-6736(15)00951-4. Epub 2015 Dec 18. Lancet. 2015. PMID: 26738716 No abstract available.
Changes in the primary outcome in Ebola vaccine trial--Authors' reply.
Kieny MP, Longini IM, Henao-Restrepo AM, Watson CH, Egger M, Edmunds WJ. Kieny MP, et al. Among authors: longini im. Lancet. 2016 Apr 9;387(10027):1509-1510. doi: 10.1016/S0140-6736(16)00686-3. Epub 2016 Apr 7. Lancet. 2016. PMID: 27115974 No abstract available.
Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!).
Henao-Restrepo AM, Camacho A, Longini IM, Watson CH, Edmunds WJ, Egger M, Carroll MW, Dean NE, Diatta I, Doumbia M, Draguez B, Duraffour S, Enwere G, Grais R, Gunther S, Gsell PS, Hossmann S, Watle SV, Kondé MK, Kéïta S, Kone S, Kuisma E, Levine MM, Mandal S, Mauget T, Norheim G, Riveros X, Soumah A, Trelle S, Vicari AS, Røttingen JA, Kieny MP. Henao-Restrepo AM, et al. Among authors: longini im. Lancet. 2017 Feb 4;389(10068):505-518. doi: 10.1016/S0140-6736(16)32621-6. Epub 2016 Dec 23. Lancet. 2017. PMID: 28017403 Free PMC article. Clinical Trial.
Design of vaccine efficacy trials during public health emergencies.
Dean NE, Gsell PS, Brookmeyer R, De Gruttola V, Donnelly CA, Halloran ME, Jasseh M, Nason M, Riveros X, Watson CH, Henao-Restrepo AM, Longini IM. Dean NE, et al. Among authors: longini im. Sci Transl Med. 2019 Jul 3;11(499):eaat0360. doi: 10.1126/scitranslmed.aat0360. Sci Transl Med. 2019. PMID: 31270270 Free PMC article. Review.
Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks.
Dean NE, Gsell PS, Brookmeyer R, Crawford FW, Donnelly CA, Ellenberg SS, Fleming TR, Halloran ME, Horby P, Jaki T, Krause PR, Longini IM, Mulangu S, Muyembe-Tamfum JJ, Nason MC, Smith PG, Wang R, Henao-Restrepo AM, De Gruttola V. Dean NE, et al. Among authors: longini im. N Engl J Med. 2020 Apr 2;382(14):1366-1369. doi: 10.1056/NEJMsb1905390. N Engl J Med. 2020. PMID: 32242365 Free PMC article. No abstract available.
COVID-19 vaccine trials should seek worthwhile efficacy.
Krause P, Fleming TR, Longini I, Henao-Restrepo AM, Peto R; World Health Organization Solidarity Vaccines Trial Expert Group. Krause P, et al. Lancet. 2020 Sep 12;396(10253):741-743. doi: 10.1016/S0140-6736(20)31821-3. Epub 2020 Aug 27. Lancet. 2020. PMID: 32861315 Free PMC article. No abstract available.
233 results