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Pyrophosphorolysis detects B-RAF mutations in primary uveal melanoma.
Maat W, Kilic E, Luyten GP, de Klein A, Jager MJ, Gruis NA, Van der Velden PA. Maat W, et al. Among authors: luyten gp. Invest Ophthalmol Vis Sci. 2008 Jan;49(1):23-7. doi: 10.1167/iovs.07-0722. Invest Ophthalmol Vis Sci. 2008. PMID: 18172070
Digital PCR validates 8q dosage as prognostic tool in uveal melanoma.
Versluis M, de Lange MJ, van Pelt SI, Ruivenkamp CA, Kroes WG, Cao J, Jager MJ, Luyten GP, van der Velden PA. Versluis M, et al. Among authors: luyten gp. PLoS One. 2015 Mar 12;10(3):e0116371. doi: 10.1371/journal.pone.0116371. eCollection 2015. PLoS One. 2015. PMID: 25764247 Free PMC article.
Serous Retinopathy Associated with Mitogen-Activated Protein Kinase Kinase Inhibition (Binimetinib) for Metastatic Cutaneous and Uveal Melanoma.
van Dijk EH, van Herpen CM, Marinkovic M, Haanen JB, Amundson D, Luyten GP, Jager MJ, Kapiteijn EH, Keunen JE, Adamus G, Boon CJ. van Dijk EH, et al. Among authors: luyten gp. Ophthalmology. 2015 Sep;122(9):1907-16. doi: 10.1016/j.ophtha.2015.05.027. Epub 2015 Jun 26. Ophthalmology. 2015. PMID: 26123090 Clinical Trial.
Isolated (hypoxic) hepatic perfusion with high-dose chemotherapy in patients with unresectable liver metastases of uveal melanoma: results from two experienced centres.
de Leede EM, Burgmans MC, Kapiteijn E, Luyten GP, Jager MJ, Tijl FG, Hartgrink HH, Grünhagen DJ, Rothbarth J, van de Velde CJ, Verhoef C, Vahrmeijer AL. de Leede EM, et al. Among authors: luyten gp. Melanoma Res. 2016 Dec;26(6):588-594. doi: 10.1097/CMR.0000000000000286. Melanoma Res. 2016. PMID: 27513071
Digital PCR-Based T-cell Quantification-Assisted Deconvolution of the Microenvironment Reveals that Activated Macrophages Drive Tumor Inflammation in Uveal Melanoma.
de Lange MJ, Nell RJ, Lalai RN, Versluis M, Jordanova ES, Luyten GPM, Jager MJ, van der Burg SH, Zoutman WH, van Hall T, van der Velden PA. de Lange MJ, et al. Mol Cancer Res. 2018 Dec;16(12):1902-1911. doi: 10.1158/1541-7786.MCR-18-0114. Epub 2018 Aug 9. Mol Cancer Res. 2018. PMID: 30093564
Two Late Recurrences of Conjunctival Melanoma.
Brouwer NJ, Genders SW, Marinkovic M, van Duinen SG, Jager MJ, Luyten GPM. Brouwer NJ, et al. Ocul Oncol Pathol. 2019 Jun;5(4):262-266. doi: 10.1159/000494978. Epub 2018 Dec 12. Ocul Oncol Pathol. 2019. PMID: 31367588 Free PMC article.
The RAS-BRAF kinase pathway is not involved in uveal melanoma.
Kiliç E, Brüggenwirth HT, Verbiest MM, Zwarthoff EC, Mooy NM, Luyten GP, de Klein A. Kiliç E, et al. Among authors: luyten gp. Melanoma Res. 2004 Jun;14(3):203-5. doi: 10.1097/01.cmr.0000130006.46885.a0. Melanoma Res. 2004. PMID: 15179189
188 results