Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2020 1
2021 9
2022 3
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

14 results

Results by year

Filters applied: . Clear all
Page 1
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.
Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li JZ, Khatri A, Chu HY; MGH COVID-19 Collection & Processing Team; Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Shrock E, et al. Science. 2020 Nov 27;370(6520):eabd4250. doi: 10.1126/science.abd4250. Epub 2020 Sep 29. Science. 2020. PMID: 32994364 Free PMC article.
Understanding humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for improving diagnostics, therapeutics, and vaccines. Deep serological profiling of 232 coronavirus d …
Understanding humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS- …
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs.
Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, Leistritz-Edwards D, Durkin MR, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Carulli IP, Chea VA, Chandrashekar A, Bozkus CC, Carrington M; MGH COVID-19 Collection & Processing Team; Bhardwaj N, Barouch DH, Sette A, Maus MV, Rice CM, Clauser KR, Keskin DB, Pregibon DC, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC. Weingarten-Gabbay S, et al. Cell. 2021 Jul 22;184(15):3962-3980.e17. doi: 10.1016/j.cell.2021.05.046. Epub 2021 Jun 3. Cell. 2021. PMID: 34171305 Free PMC article.
T cell-mediated immunity plays an important role in controlling SARS-CoV-2 infection, but the repertoire of naturally processed and presented viral epitopes on class I human leukocyte antigen (HLA-I) remains uncharacterized. Here, we report the first HLA-I im …
T cell-mediated immunity plays an important role in controlling SARS-CoV-2 infection, but the repertoire of naturally p …
Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection.
Silverstein NJ, Wang Y, Manickas-Hill Z, Carbone C, Dauphin A, Boribong BP, Loiselle M, Davis J, Leonard MM, Kuri-Cervantes L; MGH COVID-19 Collection & Processing Team; Meyer NJ, Betts MR, Li JZ, Walker BD, Yu XG, Yonker LM, Luban J. Silverstein NJ, et al. Elife. 2022 Mar 11;11:e74681. doi: 10.7554/eLife.74681. Elife. 2022. PMID: 35275061 Free PMC article.
BACKGROUND: Risk of severe COVID-19 increases with age, is greater in males, and is associated with lymphopenia, but not with higher burden of SARS-CoV-2. ...CONCLUSIONS: These results suggest that, by promoting disease tolerance, homeostatic IL …
BACKGROUND: Risk of severe COVID-19 increases with age, is greater in males, and is associated with lymphopenia, but not with …
SARS-CoV-2 epitope-specific CD4(+) memory T cell responses across COVID-19 disease severity and antibody durability.
Nelson RW, Chen Y, Venezia OL, Majerus RM, Shin DS; MGH COVID-19 Collection & Processing Team; Carrington MN, Yu XG, Wesemann DR, Moon JJ, Luster AD. Nelson RW, et al. Sci Immunol. 2022 Jul 22;7(73):eabl9464. doi: 10.1126/sciimmunol.abl9464. Epub 2022 Jul 22. Sci Immunol. 2022. PMID: 35857584 Free PMC article.
CD4(+) T cells are central to long-term immunity against viruses through the functions of T helper 1 (T(H)1) and T follicular helper (T(FH)) cell subsets. To better understand the role of these subsets in coronavirus disease 2019 (COVID-19) immunity, we condu …
CD4(+) T cells are central to long-term immunity against viruses through the functions of T helper 1 (T(H)1) and T follicular helper (T(FH)) …
Profound Treg perturbations correlate with COVID-19 severity.
Galván-Peña S, Leon J, Chowdhary K, Michelson DA, Vijaykumar B, Yang L, Magnuson AM, Chen F, Manickas-Hill Z, Piechocka-Trocha A, Worrall DP, Hall KE, Ghebremichael M, Walker BD, Li JZ, Yu XG; MGH COVID-19 Collection & Processing Team; Mathis D, Benoist C. Galván-Peña S, et al. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2111315118. doi: 10.1073/pnas.2111315118. Proc Natl Acad Sci U S A. 2021. PMID: 34433692 Free PMC article.
The hallmark of severe COVID-19 is an uncontrolled inflammatory response, resulting from poorly understood immunological dysfunction. ...A screen for candidate agents revealed that IL-6 and IL-18 may individually contribute different facets of these COVID- …
The hallmark of severe COVID-19 is an uncontrolled inflammatory response, resulting from poorly understood immunological dysfu …
Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19.
Schmaier AA, Pajares Hurtado GM, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Shapiro NI, Gerszten RE, Yu XG; MGH COVID-19 Collection and Processing Team; Peters KG, Flaumenhaft R, Parikh SM. Schmaier AA, et al. JCI Insight. 2021 Oct 22;6(20):e151527. doi: 10.1172/jci.insight.151527. JCI Insight. 2021. PMID: 34506304 Free PMC article.
Pharmacologic activation of Tie2 with the small molecule AKB-9778 reversed the prothrombotic state induced by COVID-19 plasma in primary endothelial cells. Lung autopsies from patients with COVID-19 demonstrated a prothrombotic endothelial signature. . …
Pharmacologic activation of Tie2 with the small molecule AKB-9778 reversed the prothrombotic state induced by COVID-19 plasma …
Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19.
Schmaier AA, Hurtado GP, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Gerszten RE, Yu XG; MGH COVID-19 Collection and Processing Team; Peters K, Flaumenhaft R, Parikh SM. Schmaier AA, et al. medRxiv [Preprint]. 2021 May 17:2021.05.13.21257070. doi: 10.1101/2021.05.13.21257070. medRxiv. 2021. PMID: 34031665 Free PMC article. Updated. Preprint.
Pharmacologic activation of Tie2 with the small molecule AKB-9778 reversed the prothrombotic state induced by COVID-19 plasma in primary endothelial cells. On lung autopsy specimens from COVID-19 patients, we found a prothrombotic endothelial signature …
Pharmacologic activation of Tie2 with the small molecule AKB-9778 reversed the prothrombotic state induced by COVID-19 plasma …
Plasma P-selectin is an early marker of thromboembolism in COVID-19.
Fenyves BG, Mehta A, Kays KR; MGH COVID-19 Collection & Processing Team; Goldberg MB, Hacohen N, Filbin MR. Fenyves BG, et al. medRxiv [Preprint]. 2021 Jul 14:2021.07.10.21260293. doi: 10.1101/2021.07.10.21260293. medRxiv. 2021. PMID: 34282425 Free PMC article. Updated. Preprint.
Coagulopathy and thromboembolism are known complications of SARS-CoV-2 infection. The mechanisms of COVID-19-associated hematologic complications involve endothelial cell and platelet dysfunction and have been intensively studied. ...We included …
Coagulopathy and thromboembolism are known complications of SARS-CoV-2 infection. The mechanisms of COVID-19 …
Plasma P-selectin is an early marker of thromboembolism in COVID-19.
Fenyves BG, Mehta A; MGH COVID-19 Collection & Processing Team; Kays KR, Beakes C, Margolin J, Goldberg MB, Hacohen N, Filbin MR. Fenyves BG, et al. Am J Hematol. 2021 Dec 1;96(12):E468-E471. doi: 10.1002/ajh.26372. Epub 2021 Oct 16. Am J Hematol. 2021. PMID: 34622480 Free PMC article. No abstract available.
Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection.
Silverstein NJ, Wang Y, Manickas-Hill Z, Carbone C, Dauphin A, Boribong BP, Loiselle M, Davis J, Leonard MM, Kuri-Cervantes L; MGH COVID-19 Collection & Processing Team; Meyer NJ, Betts MR, Li JZ, Walker B, Yu XG, Yonker LM, Luban J. Silverstein NJ, et al. medRxiv [Preprint]. 2021 Oct 11:2021.01.14.21249839. doi: 10.1101/2021.01.14.21249839. medRxiv. 2021. PMID: 33469605 Free PMC article. Updated. Preprint.
Risk of severe COVID-19 increases with age, is greater in males, and is associated with lymphopenia, but not with higher burden of SARS-CoV-2. ...These results suggest that, by promoting disease tolerance, homeostatic ILCs decrease morbidity and …
Risk of severe COVID-19 increases with age, is greater in males, and is associated with lymphopenia, but not with higher burde …
14 results