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43 results

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Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study.
Zhou J, Singanayagam A, Goonawardane N, Moshe M, Sweeney FP, Sukhova K, Killingley B, Kalinova M, Mann AJ, Catchpole AP, Barer MR, Ferguson NM, Chiu C, Barclay WS. Zhou J, et al. Lancet Microbe. 2023 Aug;4(8):e579-e590. doi: 10.1016/S2666-5247(23)00101-5. Epub 2023 Jun 9. Lancet Microbe. 2023. PMID: 37307844 Free PMC article. Clinical Trial.
Respiratory viruses: New frontiers-a Keystone Symposia report.
Cable J, Sun J, Cheon IS, Vaughan AE, Castro IA, Stein SR, López CB, Gostic KM, Openshaw PJM, Ellebedy AH, Wack A, Hutchinson E, Thomas MM, Langlois RA, Lingwood D, Baker SF, Folkins M, Foxman EF, Ward AB, Schwemmle M, Russell AB, Chiu C, Ganti K, Subbarao K, Sheahan TP, Penaloza-MacMaster P, Eddens T. Cable J, et al. Ann N Y Acad Sci. 2023 Apr;1522(1):60-73. doi: 10.1111/nyas.14958. Epub 2023 Feb 1. Ann N Y Acad Sci. 2023. PMID: 36722473 Free PMC article.
Divergent age-related humoral correlates of protection against respiratory syncytial virus infection in older and young adults: a pilot, controlled, human infection challenge model.
Ascough S, Dayananda P, Kalyan M, Kuong SU, Gardener Z, Bergstrom E, Paterson S, Kar S, Avadhan V, Thwaites R, Sanchez Sevilla Uruchurtu A, Ruckwardt TJ, Chen M, Nair D, Derrien-Colemyn A, Graham BS, Begg M, Hessel E, Openshaw P, Chiu C. Ascough S, et al. Lancet Healthy Longev. 2022 Jun;3(6):e405-e416. doi: 10.1016/S2666-7568(22)00103-9. Epub 2022 Jun 9. Lancet Healthy Longev. 2022. PMID: 36098319 Free article.
A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study.
Osowicki J, Azzopardi KI, Fabri L, Frost HR, Rivera-Hernandez T, Neeland MR, Whitcombe AL, Grobler A, Gutman SJ, Baker C, Wong JMF, Lickliter JD, Waddington CS, Pandey M, Schuster T, Cheng AC, Pollard AJ, McCarthy JS, Good MF, Dale JB, Batzloff M, Moreland NJ, Walker MJ, Carapetis JR, Smeesters PR, Steer AC. Osowicki J, et al. Lancet Microbe. 2021 Jul;2(7):e291-e299. doi: 10.1016/S2666-5247(20)30240-8. Epub 2021 Apr 15. Lancet Microbe. 2021. PMID: 35544165 Free article.
Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study.
Barker C, Collet K, Gbesemete D, Piggin M, Watson D, Pristerà P, Lawerence W, Smith E, Bahrami-Hessari M, Johnson H, Baker K, Qavi A, McGrath C, Chiu C, Read RC, Ward H. Barker C, et al. Wellcome Open Res. 2022 Feb 10;7:49. doi: 10.12688/wellcomeopenres.17516.1. eCollection 2022. Wellcome Open Res. 2022. PMID: 35321005 Free PMC article.
Ethics review of COVID-19 human challenge studies: A joint HRA/WHO workshop.
Williams E, Craig K, Chiu C, Davies H, Ellis S, Emerson C, Jamrozik E, Jefford M, Kang G, Kapulu M, Kolstoe SE, Littler K, Lockett A, Elena Rey, Messer J, McShane H, Saenz C, Selgelid MJ, Shah S, Smith PG, Yamazaki N. Williams E, et al. Vaccine. 2022 Jun 9;40(26):3484-3489. doi: 10.1016/j.vaccine.2022.02.004. Epub 2022 Feb 14. Vaccine. 2022. PMID: 35210119 Free PMC article.
Prior upregulation of interferon pathways in the nasopharynx impacts viral shedding following live attenuated influenza vaccine challenge in children.
Costa-Martins AG, Mane K, Lindsey BB, Ogava RLT, Castro Í, Jagne YJ, Sallah HJ, Armitage EP, Jarju S, Ahadzie B, Ellis-Watson R, Tregoning JS, Bingle CD, Bogaert D, Clarke E, Ordovas-Montanes J, Jeffries D, Kampmann B, Nakaya HI, de Silva TI. Costa-Martins AG, et al. Cell Rep Med. 2021 Dec 9;2(12):100465. doi: 10.1016/j.xcrm.2021.100465. eCollection 2021 Dec 21. Cell Rep Med. 2021. PMID: 35028607 Free PMC article. Clinical Trial.
Using correlates to accelerate vaccinology.
Openshaw PJM. Openshaw PJM. Science. 2022 Jan 7;375(6576):22-23. doi: 10.1126/science.abn0007. Epub 2022 Jan 6. Science. 2022. PMID: 34990231
43 results