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Year Number of Results
2020 7
2021 5
2022 5
2023 5
2024 1

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23 results

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Page 1
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
Shilts J, Crozier TWM, Teixeira-Silva A, Gabaev I, Gerber PP, Greenwood EJD, Watson SJ, Ortmann BM, Gawden-Bone CM, Pauzaite T, Hoffmann M, Nathan JA, Pöhlmann S, Matheson NJ, Lehner PJ, Wright GJ. Shilts J, et al. PLoS Biol. 2023 Feb 3;21(2):e3001959. doi: 10.1371/journal.pbio.3001959. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36735681 Free PMC article.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.
Sparbier CE, Gillespie A, Gomez J, Kumari N, Motazedian A, Chan KL, Bell CC, Gilan O, Chan YC, Popp S, Gough DJ, Eckersley-Maslin MA, Dawson SJ, Lehner PJ, Sutherland KD, Ernst P, McGeehan GM, Lam EYN, Burr ML, Dawson MA. Sparbier CE, et al. Nat Cell Biol. 2023 Feb;25(2):258-272. doi: 10.1038/s41556-022-01056-x. Epub 2023 Jan 12. Nat Cell Biol. 2023. PMID: 36635503 Free PMC article.
Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion.
Crozier TWM, Greenwood EJD, Williamson JC, Guo W, Porter LM, Gabaev I, Teixeira-Silva A, Grice GL, Wickenhagen A, Stanton RJ, Wang ECY, Wilson SJ, Matheson NJ, Nathan JA, McCaughan F, Lehner PJ. Crozier TWM, et al. Wellcome Open Res. 2022 Sep 7;7:224. doi: 10.12688/wellcomeopenres.17946.1. eCollection 2022. Wellcome Open Res. 2022. PMID: 36483314 Free PMC article.
EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
Randzavola LO, Mortimer PM, Garside E, Dufficy ER, Schejtman A, Roumelioti G, Yu L, Pardo M, Spirohn K, Tolley C, Brandt C, Harcourt K, Nichols E, Nahorski M, Woods G, Williamson JC, Suresh S, Sowerby JM, Matsumoto M, Santos CXC, Kiar CS, Mukhopadhyay S, Rae WM, Dougan GJ, Grainger J, Lehner PJ, Calderwood MA, Choudhary J, Clare S, Speak A, Santilli G, Bateman A, Smith KGC, Magnani F, Thomas DC. Randzavola LO, et al. Elife. 2022 Nov 24;11:e76387. doi: 10.7554/eLife.76387. Elife. 2022. PMID: 36421765 Free PMC article.
Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor.
Perera MR, Greenwood EJD, Crozier TWM, Elder EG, Schmitt J, Crump CM, Lehner PJ, Wills MR, Sinclair JH; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research COVID BioResource Collaboration. Perera MR, et al. J Infect Dis. 2023 Feb 14;227(4):543-553. doi: 10.1093/infdis/jiac452. J Infect Dis. 2023. PMID: 36408607 Free PMC article.
Evidence of previous SARS-CoV-2 infection in seronegative patients with long COVID.
Krishna BA, Lim EY, Mactavous L; NIHR BioResource Team; Lyons PA, Doffinger R, Bradley JR, Smith KGC, Sinclair J, Matheson NJ, Lehner PJ, Wills MR, Sithole N. Krishna BA, et al. EBioMedicine. 2022 Jul;81:104129. doi: 10.1016/j.ebiom.2022.104129. Epub 2022 Jun 27. EBioMedicine. 2022. PMID: 35772216 Free PMC article.
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies.
Fielding CA, Sabberwal P, Williamson JC, Greenwood EJD, Crozier TWM, Zelek W, Seow J, Graham C, Huettner I, Edgeworth JD, Price DA, Morgan PB, Ladell K, Eberl M, Humphreys IR, Merrick B, Doores K, Wilson SJ, Lehner PJ, Wang ECY, Stanton RJ. Fielding CA, et al. Elife. 2022 May 19;11:e74489. doi: 10.7554/eLife.74489. Elife. 2022. PMID: 35587364 Free PMC article.
23 results