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CDK1 dependent phosphorylation of hTERT contributes to cancer progression.
Yasukawa M, Ando Y, Yamashita T, Matsuda Y, Shoji S, Morioka MS, Kawaji H, Shiozawa K, Machitani M, Abe T, Yamada S, Kaneko MK, Kato Y, Furuta Y, Kondo T, Shirouzu M, Hayashizaki Y, Kaneko S, Masutomi K. Yasukawa M, et al. Among authors: machitani m. Nat Commun. 2020 Mar 25;11(1):1557. doi: 10.1038/s41467-020-15289-7. Nat Commun. 2020. PMID: 32214089 Free PMC article.
Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs.
Matsuda Y, Yamashita T, Ye J, Yasukawa M, Yamakawa K, Mukai Y, Machitani M, Daigo Y, Miyagi Y, Yokose T, Oshima T, Ito H, Morinaga S, Kishida T, Minamoto T, Yamada S, Takei J, Kaneko MK, Kojima M, Kaneko S, Masaki T, Hirata M, Haba R, Kontani K, Kanaji N, Miyatake N, Okano K, Kato Y, Masutomi K. Matsuda Y, et al. Among authors: machitani m. J Pathol. 2022 Jun;257(2):172-185. doi: 10.1002/path.5876. Epub 2022 Mar 23. J Pathol. 2022. PMID: 35094384 Free PMC article.
22 results