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Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals.
Burgdorf KS, Gjesing AP, Grarup N, Justesen JM, Sandholt CH, Witte DR, Jørgensen T, Madsbad S, Hansen T, Pedersen O. Burgdorf KS, et al. Among authors: madsbad s. Diabetologia. 2012 Jan;55(1):105-13. doi: 10.1007/s00125-011-2320-4. Epub 2011 Sep 28. Diabetologia. 2012. PMID: 21953277 Clinical Trial.
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Sparsø T, Andersen G, Nielsen T, Burgdorf KS, Gjesing AP, Nielsen AL, Albrechtsen A, Rasmussen SS, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O. Sparsø T, et al. Among authors: madsbad s. Diabetologia. 2008 Jan;51(1):70-5. doi: 10.1007/s00125-007-0865-z. Epub 2007 Nov 16. Diabetologia. 2008. PMID: 18008060
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.
Sparsø T, Andersen G, Albrechtsen A, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Wasson J, Permutt MA, Glaser B, Madsbad S, Pedersen O, Hansen T. Sparsø T, et al. Among authors: madsbad s. Diabetologia. 2008 Sep;51(9):1646-52. doi: 10.1007/s00125-008-1064-2. Epub 2008 Jun 21. Diabetologia. 2008. PMID: 18568334
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.
Sparsø T, Grarup N, Andreasen C, Albrechtsen A, Holmkvist J, Andersen G, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O. Sparsø T, et al. Among authors: madsbad s. Diabetologia. 2009 Jul;52(7):1308-14. doi: 10.1007/s00125-009-1362-3. Epub 2009 Apr 29. Diabetologia. 2009. PMID: 19404609
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1.
Torekov SS, Ma L, Grarup N, Hartmann B, Hainerová IA, Kielgast U, Kissow H, Rosenkilde M; GIANT Consortium; Lebl J, Witte DR, Jørgensen T, Sandbaek A, Lauritzen T, Madsen OD, Wang J, Linneberg A, Madsbad S, Holst JJ, Hansen T, Pedersen O. Torekov SS, et al. Among authors: madsbad s. Diabetologia. 2011 Nov;54(11):2820-31. doi: 10.1007/s00125-011-2265-7. Epub 2011 Aug 7. Diabetologia. 2011. PMID: 21822931
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.
Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsbøll T, Hansen T, Madsbad S, Holst JJ, Vølund A, Poulsen P, Groop L, Pedersen O, Vaag AA. Pilgaard K, et al. Among authors: madsbad s. Diabetologia. 2009 Jul;52(7):1298-307. doi: 10.1007/s00125-009-1307-x. Epub 2009 Mar 14. Diabetologia. 2009. PMID: 19288077 Free article.
No interactions between polymorphisms in the beta3-adrenergic receptor gene and the PPAR-gamma gene on the risk of the insulin resistance syndrome in the Danish MONICA cohort.
Frederiksen L, Brødbaek K, Fenger M, Madsbad S, Urhammer SA, Jørgensen T, Borch-Johnsen K. Frederiksen L, et al. Among authors: madsbad s. Diabetologia. 2003 May;46(5):729-31. doi: 10.1007/s00125-003-1092-x. Epub 2003 May 9. Diabetologia. 2003. PMID: 12739018 No abstract available.
593 results