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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Schepens B, van Schie L, Nerinckx W, Roose K, Van Breedam W, Fijalkowska D, Devos S, Weyts W, De Cae S, Vanmarcke S, Lonigro C, Eeckhaut H, Van Herpe D, Borloo J, Oliveira AF, Catani JPP, Creytens S, De Vlieger D, Michielsen G, Marchan JCZ, Moschonas GD, Rossey I, Sedeyn K, Van Hecke A, Zhang X, Langendries L, Jacobs S, Ter Horst S, Seldeslachts L, Liesenborghs L, Boudewijns R, Thibaut HJ, Dallmeier K, Velde GV, Weynand B, Beer J, Schnepf D, Ohnemus A, Remory I, Foo CS, Abdelnabi R, Maes P, Kaptein SJF, Rocha-Pereira J, Jochmans D, Delang L, Peelman F, Staeheli P, Schwemmle M, Devoogdt N, Tersago D, Germani M, Heads J, Henry A, Popplewell A, Ellis M, Brady K, Turner A, Dombrecht B, Stortelers C, Neyts J, Callewaert N, Saelens X. Schepens B, et al. Among authors: maes p. Sci Transl Med. 2021 Nov 24;13(621):eabi7826. doi: 10.1126/scitranslmed.abi7826. Epub 2021 Nov 24. Sci Transl Med. 2021. PMID: 34609205 Free PMC article.
Growth kinetics of SARS-coronavirus in Vero E6 cells.
Keyaerts E, Vijgen L, Maes P, Neyts J, Van Ranst M. Keyaerts E, et al. Among authors: maes p. Biochem Biophys Res Commun. 2005 Apr 15;329(3):1147-51. doi: 10.1016/j.bbrc.2005.02.085. Biochem Biophys Res Commun. 2005. PMID: 15752773 Free PMC article.
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters.
Boudewijns R, Thibaut HJ, Kaptein SJF, Li R, Vergote V, Seldeslachts L, Van Weyenbergh J, De Keyzer C, Bervoets L, Sharma S, Liesenborghs L, Ma J, Jansen S, Van Looveren D, Vercruysse T, Wang X, Jochmans D, Martens E, Roose K, De Vlieger D, Schepens B, Van Buyten T, Jacobs S, Liu Y, Martí-Carreras J, Vanmechelen B, Wawina-Bokalanga T, Delang L, Rocha-Pereira J, Coelmont L, Chiu W, Leyssen P, Heylen E, Schols D, Wang L, Close L, Matthijnssens J, Van Ranst M, Compernolle V, Schramm G, Van Laere K, Saelens X, Callewaert N, Opdenakker G, Maes P, Weynand B, Cawthorne C, Vande Velde G, Wang Z, Neyts J, Dallmeier K. Boudewijns R, et al. Among authors: maes p. Nat Commun. 2020 Nov 17;11(1):5838. doi: 10.1038/s41467-020-19684-y. Nat Commun. 2020. PMID: 33203860 Free PMC article.
Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2.
Baggen J, Persoons L, Vanstreels E, Jansen S, Van Looveren D, Boeckx B, Geudens V, De Man J, Jochmans D, Wauters J, Wauters E, Vanaudenaerde BM, Lambrechts D, Neyts J, Dallmeier K, Thibaut HJ, Jacquemyn M, Maes P, Daelemans D. Baggen J, et al. Among authors: maes p. Nat Genet. 2021 Apr;53(4):435-444. doi: 10.1038/s41588-021-00805-2. Epub 2021 Mar 8. Nat Genet. 2021. PMID: 33686287
The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways.
Laporte M, Raeymaekers V, Van Berwaer R, Vandeput J, Marchand-Casas I, Thibaut HJ, Van Looveren D, Martens K, Hoffmann M, Maes P, Pöhlmann S, Naesens L, Stevaert A. Laporte M, et al. Among authors: maes p. PLoS Pathog. 2021 Apr 22;17(4):e1009500. doi: 10.1371/journal.ppat.1009500. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33886690 Free PMC article.
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters.
Abdelnabi R, Boudewijns R, Foo CS, Seldeslachts L, Sanchez-Felipe L, Zhang X, Delang L, Maes P, Kaptein SJF, Weynand B, Vande Velde G, Neyts J, Dallmeier K. Abdelnabi R, et al. Among authors: maes p. EBioMedicine. 2021 Jun;68:103403. doi: 10.1016/j.ebiom.2021.103403. Epub 2021 May 25. EBioMedicine. 2021. PMID: 34049240 Free PMC article.
SARS-CoV-2 neutralising antibody testing in Europe: towards harmonisation of neutralising antibody titres for better use of convalescent plasma and comparability of trial data.
Nguyen D, Simmonds P, Steenhuis M, Wouters E, Desmecht D, Garigliany M, Romano M, Barbezange C, Maes P, Van Holm B, Mendoza J, Oyonarte S, Fomsgaard A, Lassaunière R, Zusinaite E, Resman Rus K, Avšič-Županc T, Reimerink JH, Brouwer F, Hoogerwerf M, Reusken CB, Grodeland G, Le Cam S, Gallian P, Amroun A, Brisbarre N, Martinaud C, Leparc Goffart I, Schrezenmeier H, Feys HB, van der Schoot CE, Harvala H. Nguyen D, et al. Among authors: maes p. Euro Surveill. 2021 Jul;26(27):2100568. doi: 10.2807/1560-7917.ES.2021.26.27.2100568. Euro Surveill. 2021. PMID: 34240697 Free PMC article.
434 results