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Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies.
Cell Host Microbe. 2021 Mar 10;29(3):463-476.e6. doi: 10.1016/j.chom.2021.02.003. Epub 2021 Feb 8.
Cell Host Microbe. 2021.
PMID: 33592168
Free PMC article.
Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays.
Crawford KHD, Eguia R, Dingens AS, Loes AN, Malone KD, Wolf CR, Chu HY, Tortorici MA, Veesler D, Murphy M, Pettie D, King NP, Balazs AB, Bloom JD.
Crawford KHD, et al. Among authors: malone kd.
Viruses. 2020 May 6;12(5):513. doi: 10.3390/v12050513.
Viruses. 2020.
PMID: 32384820
Free PMC article.
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Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection.
Greaney AJ, Loes AN, Gentles LE, Crawford KHD, Starr TN, Malone KD, Chu HY, Bloom JD.
Greaney AJ, et al. Among authors: malone kd.
Sci Transl Med. 2021 Jun 30;13(600):eabi9915. doi: 10.1126/scitranslmed.abi9915. Epub 2021 Jun 8.
Sci Transl Med. 2021.
PMID: 34103407
Free PMC article.
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Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design.
Ellis D, Brunette N, Crawford KHD, Walls AC, Pham MN, Chen C, Herpoldt KL, Fiala B, Murphy M, Pettie D, Kraft JC, Malone KD, Navarro MJ, Ogohara C, Kepl E, Ravichandran R, Sydeman C, Ahlrichs M, Johnson M, Blackstone A, Carter L, Starr TN, Greaney AJ, Lee KK, Veesler D, Bloom JD, King NP.
Ellis D, et al. Among authors: malone kd.
Front Immunol. 2021 Jun 29;12:710263. doi: 10.3389/fimmu.2021.710263. eCollection 2021.
Front Immunol. 2021.
PMID: 34267764
Free PMC article.
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High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination.
Dingens AS, Pratap P, Malone K, Hilton SK, Ketas T, Cottrell CA, Overbaugh J, Moore JP, Klasse PJ, Ward AB, Bloom JD.
Dingens AS, et al.
Elife. 2021 Jan 13;10:e64281. doi: 10.7554/eLife.64281.
Elife. 2021.
PMID: 33438580
Free PMC article.
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Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir.
Soh YQS, Malone KD, Eguia RT, Bloom JD.
Soh YQS, et al. Among authors: malone kd.
Viruses. 2021 Jun 22;13(7):1196. doi: 10.3390/v13071196.
Viruses. 2021.
PMID: 34206520
Free PMC article.
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The SARS-CoV-2 mRNA-1273 vaccine elicits more RBD-focused neutralization, but with broader antibody binding within the RBD.
Greaney AJ, Loes AN, Gentles LE, Crawford KHD, Starr TN, Malone KD, Chu HY, Bloom JD.
Greaney AJ, et al. Among authors: malone kd.
bioRxiv [Preprint]. 2021 Apr 14:2021.04.14.439844. doi: 10.1101/2021.04.14.439844.
bioRxiv. 2021.
PMID: 33880474
Free PMC article.
Updated.
Preprint.
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