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A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues.
Dimmock JR, Padmanilayam MP, Puthucode RN, Nazarali AJ, Motaganahalli NL, Zello GA, Quail JW, Oloo EO, Kraatz HB, Prisciak JS, Allen TM, Santos CL, Balzarini J, De Clercq E, Manavathu EK. Dimmock JR, et al. Among authors: manavathu ek. J Med Chem. 2001 Feb 15;44(4):586-93. doi: 10.1021/jm0002580. J Med Chem. 2001. PMID: 11170648
Cytotoxic 1,4-bis(2-oxo-1-cycloalkylmethylene)benzenes and related compounds.
Dimmock JR, Jha A, Kumar P, Zello GA, Quail JW, Oloo EO, Oucharek JJ, Pasha MK, Seitz D, Sharma RK, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: manavathu ek. Eur J Med Chem. 2002 Jan;37(1):35-44. doi: 10.1016/s0223-5234(01)01294-6. Eur J Med Chem. 2002. PMID: 11841873
Cytotoxic 1,3-diarylidene-2-tetralones and related compounds.
Dimmock JR, Padmanilyam MP, Zello GA, Quail JW, Oloo EO, Prisciak JS, Kraatz HB, Cherkasov A, Lee JS, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: manavathu ek. Eur J Med Chem. 2002 Oct;37(10):813-24. doi: 10.1016/s0223-5234(02)01402-2. Eur J Med Chem. 2002. PMID: 12446039
Cytotoxic analogues of 2,6-bis(arylidene)cyclohexanones.
Dimmock JR, Padmanilayam MP, Zello GA, Nienaber KH, Allen TM, Santos CL, De Clercq E, Balzarini J, Manavathu EK, Stables JP. Dimmock JR, et al. Among authors: manavathu ek. Eur J Med Chem. 2003 Feb;38(2):169-77. doi: 10.1016/s0223-5234(02)01444-7. Eur J Med Chem. 2003. PMID: 12620661
Cytotoxic 5-aryl-1-(4-nitrophenyl)-3-oxo-1,4-pentadienes mounted on alicyclic scaffolds.
Das U, Gul HI, Alcorn J, Shrivastav A, George T, Sharma RK, Nienaber KH, De Clercq E, Balzarini J, Kawase M, Kan N, Tanaka T, Tani S, Werbovetz KA, Yakovich AJ, Manavathu EK, Stables JP, Dimmock JR. Das U, et al. Among authors: manavathu ek. Eur J Med Chem. 2006 May;41(5):577-85. doi: 10.1016/j.ejmech.2005.12.014. Epub 2006 Apr 3. Eur J Med Chem. 2006. PMID: 16581158
Cytotoxic activities of Mannich bases of chalcones and related compounds.
Dimmock JR, Kandepu NM, Hetherington M, Quail JW, Pugazhenthi U, Sudom AM, Chamankhah M, Rose P, Pass E, Allen TM, Halleran S, Szydlowski J, Mutus B, Tannous M, Manavathu EK, Myers TG, De Clercq E, Balzarini J. Dimmock JR, et al. Among authors: manavathu ek. J Med Chem. 1998 Mar 26;41(7):1014-26. doi: 10.1021/jm970432t. J Med Chem. 1998. PMID: 9544201
Cytotoxic 4'-aminochalcones and related compounds.
Dimmock JR, Jha A, Zello GA, Allen TM, Santos CL, Balzarini J, De Clercq E, Manavathu EK, Stables JP. Dimmock JR, et al. Among authors: manavathu ek. Pharmazie. 2003 Apr;58(4):227-32. Pharmazie. 2003. PMID: 12749401
80 results