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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Cell Rep. 2014 Nov 20;9(4):1482-94. doi: 10.1016/j.celrep.2014.10.041. Epub 2014 Nov 13.
Cell Rep. 2014.
PMID: 25456137
Free PMC article.
New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins.
Mannion N, Arieti F, Gallo A, Keegan LP, O'Connell MA.
Mannion N, et al.
Biomolecules. 2015 Sep 30;5(4):2338-62. doi: 10.3390/biom5042338.
Biomolecules. 2015.
PMID: 26437436
Free PMC article.
Review.
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Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Rice GI, Kasher PR, Forte GM, Mannion NM, Greenwood SM, Szynkiewicz M, Dickerson JE, Bhaskar SS, Zampini M, Briggs TA, Jenkinson EM, Bacino CA, Battini R, Bertini E, Brogan PA, Brueton LA, Carpanelli M, De Laet C, de Lonlay P, del Toro M, Desguerre I, Fazzi E, Garcia-Cazorla A, Heiberg A, Kawaguchi M, Kumar R, Lin JP, Lourenco CM, Male AM, Marques W Jr, Mignot C, Olivieri I, Orcesi S, Prabhakar P, Rasmussen M, Robinson RA, Rozenberg F, Schmidt JL, Steindl K, Tan TY, van der Merwe WG, Vanderver A, Vassallo G, Wakeling EL, Wassmer E, Whittaker E, Livingston JH, Lebon P, Suzuki T, McLaughlin PJ, Keegan LP, O'Connell MA, Lovell SC, Crow YJ.
Rice GI, et al. Among authors: mannion nm.
Nat Genet. 2012 Nov;44(11):1243-8. doi: 10.1038/ng.2414. Epub 2012 Sep 23.
Nat Genet. 2012.
PMID: 23001123
Free PMC article.
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The Epitranscriptome and Innate Immunity.
O'Connell MA, Mannion NM, Keegan LP.
O'Connell MA, et al. Among authors: mannion nm.
PLoS Genet. 2015 Dec 10;11(12):e1005687. doi: 10.1371/journal.pgen.1005687. eCollection 2015 Dec.
PLoS Genet. 2015.
PMID: 26658668
Free PMC article.
Review.
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A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival.
Massett ME, Monaghan L, Patterson S, Mannion N, Bunschoten RP, Hoose A, Marmiroli S, Liskamp RMJ, Jørgensen HG, Vetrie D, Michie AM, Huang X.
Massett ME, et al.
Cell Death Dis. 2021 Jun 3;12(6):573. doi: 10.1038/s41419-021-03738-0.
Cell Death Dis. 2021.
PMID: 34083515
Free PMC article.
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Pulse Oximetry for Monitoring Patients with Covid-19 at Home - A Pragmatic, Randomized Trial.
Lee KC, Morgan AU, Chaiyachati KH, Asch DA, Xiong RA, Do D, Kilaru AS, Lam D, Parambath A, Friedman AB, Meisel ZF, Snider CK, Chisholm DL, Kelly S, Hemmons JE, Abdel-Rahman D, Ebert J, Ghosh M, Reilly J, O'Malley CJ, Hahn L, Mannion NM, Huffenberger AM, McGinley S, Balachandran M, Khan N, Shea JA, Mitra N, Delgado MK.
Lee KC, et al. Among authors: mannion nm.
N Engl J Med. 2022 May 12;386(19):1857-1859. doi: 10.1056/NEJMc2201541. Epub 2022 Apr 6.
N Engl J Med. 2022.
PMID: 35385625
Free PMC article.
Clinical Trial.
No abstract available.
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