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Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma.
Walsh AM, Kapoor GS, Buonato JM, Mathew LK, Bi Y, Davuluri RV, Martinez-Lage M, Simon MC, O'Rourke DM, Lazzara MJ. Walsh AM, et al. Mol Cancer Res. 2015 Aug;13(8):1227-37. doi: 10.1158/1541-7786.MCR-14-0183-T. Epub 2015 May 1. Mol Cancer Res. 2015. PMID: 25934697 Free PMC article.
Immune landscapes associated with different glioblastoma molecular subtypes.
Martinez-Lage M, Lynch TM, Bi Y, Cocito C, Way GP, Pal S, Haller J, Yan RE, Ziober A, Nguyen A, Kandpal M, O'Rourke DM, Greenfield JP, Greene CS, Davuluri RV, Dahmane N. Martinez-Lage M, et al. Acta Neuropathol Commun. 2019 Nov 29;7(1):203. doi: 10.1186/s40478-019-0803-6. Acta Neuropathol Commun. 2019. PMID: 31815646 Free PMC article.
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, Zheng Z, Levine BL, Okada H, June CH, Brogdon JL, Maus MV. O'Rourke DM, et al. Sci Transl Med. 2017 Jul 19;9(399):eaaa0984. doi: 10.1126/scitranslmed.aaa0984. Sci Transl Med. 2017. PMID: 28724573 Free PMC article. Clinical Trial.
Histopathology-validated machine learning radiographic biomarker for noninvasive discrimination between true progression and pseudo-progression in glioblastoma.
Akbari H, Rathore S, Bakas S, Nasrallah MP, Shukla G, Mamourian E, Rozycki M, Bagley SJ, Rudie JD, Flanders AE, Dicker AP, Desai AS, O'Rourke DM, Brem S, Lustig R, Mohan S, Wolf RL, Bilello M, Martinez-Lage M, Davatzikos C. Akbari H, et al. Cancer. 2020 Jun 1;126(11):2625-2636. doi: 10.1002/cncr.32790. Epub 2020 Mar 4. Cancer. 2020. PMID: 32129893 Free PMC article.
115 results