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The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia.
Van der Meulen J, Sanghvi V, Mavrakis K, Durinck K, Fang F, Matthijssens F, Rondou P, Rosen M, Pieters T, Vandenberghe P, Delabesse E, Lammens T, De Moerloose B, Menten B, Van Roy N, Verhasselt B, Poppe B, Benoit Y, Taghon T, Melnick AM, Speleman F, Wendel HG, Van Vlierberghe P. Van der Meulen J, et al. Among authors: mavrakis k. Blood. 2015 Jan 1;125(1):13-21. doi: 10.1182/blood-2014-05-577270. Epub 2014 Oct 15. Blood. 2015. PMID: 25320243 Free PMC article.
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, Teruya-Feldstein J, Kelliher MA, Speleman F, Porco JA Jr, Pelletier J, Rätsch G, Wendel HG. Wolfe AL, et al. Among authors: mavrakis kj. Nature. 2014 Sep 4;513(7516):65-70. doi: 10.1038/nature13485. Epub 2014 Jul 27. Nature. 2014. PMID: 25079319 Free PMC article.
Translational control and cancer therapy.
Mavrakis KJ, Wendel HG. Mavrakis KJ, et al. Cell Cycle. 2008 Sep 15;7(18):2791-4. doi: 10.4161/cc.7.18.6683. Epub 2008 Sep 25. Cell Cycle. 2008. PMID: 18787409
Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Mavrakis KJ, Zhu H, Silva RL, Mills JR, Teruya-Feldstein J, Lowe SW, Tam W, Pelletier J, Wendel HG. Mavrakis KJ, et al. Genes Dev. 2008 Aug 15;22(16):2178-88. doi: 10.1101/gad.1690808. Genes Dev. 2008. PMID: 18708578 Free PMC article.
27 results