Maynard CJ - Search Results

1

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.

Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA, Dantuma NP, Overkleeft HS. Verdoes M, et al. Among authors: maynard cj. Chem Biol. 2006 Nov;13(11):1217-26. doi: 10.1016/j.chembiol.2006.09.013. Chem Biol. 2006. PMID: 17114003

2

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.

Maynard CJ, Böttcher C, Ortega Z, Smith R, Florea BI, Díaz-Hernández M, Brundin P, Overkleeft HS, Li JY, Lucas JJ, Dantuma NP. Maynard CJ, et al. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13986-91. doi: 10.1073/pnas.0906463106. Epub 2009 Jul 30. Proc Natl Acad Sci U S A. 2009. PMID: 19666572 Free PMC article.

3

Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

Ortega Z, Díaz-Hernández M, Maynard CJ, Hernández F, Dantuma NP, Lucas JJ. Ortega Z, et al. Among authors: maynard cj. J Neurosci. 2010 Mar 10;30(10):3675-88. doi: 10.1523/JNEUROSCI.5673-09.2010. J Neurosci. 2010. PMID: 20220001 Free PMC article.

4

Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis.

Cheroni C, Marino M, Tortarolo M, Veglianese P, De Biasi S, Fontana E, Zuccarello LV, Maynard CJ, Dantuma NP, Bendotti C. Cheroni C, et al. Among authors: maynard cj. Hum Mol Genet. 2009 Jan 1;18(1):82-96. doi: 10.1093/hmg/ddn319. Epub 2008 Sep 29. Hum Mol Genet. 2009. PMID: 18826962 Free PMC article.

5

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation.

Viswanathan J, Haapasalo A, Böttcher C, Miettinen R, Kurkinen KM, Lu A, Thomas A, Maynard CJ, Romano D, Hyman BT, Berezovska O, Bertram L, Soininen H, Dantuma NP, Tanzi RE, Hiltunen M. Viswanathan J, et al. Among authors: maynard cj. Traffic. 2011 Mar;12(3):330-48. doi: 10.1111/j.1600-0854.2010.01149.x. Epub 2011 Jan 7. Traffic. 2011. PMID: 21143716 Free PMC article.

6

Metals and amyloid-beta in Alzheimer's disease.

Maynard CJ, Bush AI, Masters CL, Cappai R, Li QX. Maynard CJ, et al. Int J Exp Pathol. 2005 Jun;86(3):147-59. doi: 10.1111/j.0959-9673.2005.00434.x. Int J Exp Pathol. 2005. PMID: 15910549 Free PMC article. Review.

7

Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice.

Li QX, Maynard C, Cappai R, McLean CA, Cherny RA, Lynch T, Culvenor JG, Trevaskis J, Tanner JE, Bailey KA, Czech C, Bush AI, Beyreuther K, Masters CL. Li QX, et al. J Neurochem. 1999 Jun;72(6):2479-87. doi: 10.1046/j.1471-4159.1999.0722479.x. J Neurochem. 1999. PMID: 10349858 Free article.

8

Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology.

Maynard CJ, Cappai R, Volitakis I, Cherny RA, Masters CL, Li QX, Bush AI. Maynard CJ, et al. J Inorg Biochem. 2006 May;100(5-6):952-62. doi: 10.1016/j.jinorgbio.2006.02.010. Epub 2006 Mar 6. J Inorg Biochem. 2006. PMID: 16574231

9

Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.

Maynard CJ, Cappai R, Volitakis I, Cherny RA, White AR, Beyreuther K, Masters CL, Bush AI, Li QX. Maynard CJ, et al. J Biol Chem. 2002 Nov 22;277(47):44670-6. doi: 10.1074/jbc.M204379200. Epub 2002 Sep 4. J Biol Chem. 2002. PMID: 12215434 Free article.

10

Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein.

Khalil Z, Poliviou H, Maynard CJ, Beyreuther K, Masters CL, Li QX. Khalil Z, et al. Among authors: maynard cj. J Alzheimers Dis. 2002 Dec;4(6):467-78. doi: 10.3233/jad-2002-4603. J Alzheimers Dis. 2002. PMID: 12515898

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