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A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitro.
Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. Xiao T, et al. Among authors: mckay lga. bioRxiv [Preprint]. 2020 Sep 18:2020.09.18.301952. doi: 10.1101/2020.09.18.301952. bioRxiv. 2020. PMID: 32995768 Free PMC article. Updated. Preprint.
A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. Xiao T, et al. Among authors: mckay lga. Nat Struct Mol Biol. 2021 Feb;28(2):202-209. doi: 10.1038/s41594-020-00549-3. Epub 2021 Jan 11. Nat Struct Mol Biol. 2021. PMID: 33432247 Free PMC article.
Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.
Tong P, Gautam A, Windsor IW, Travers M, Chen Y, Garcia N, Whiteman NB, McKay LGA, Storm N, Malsick LE, Honko AN, Lelis FJN, Habibi S, Jenni S, Cai Y, Rennick LJ, Duprex WP, McCarthy KR, Lavine CL, Zuo T, Lin J, Zuiani A, Feldman J, MacDonald EA, Hauser BM, Griffths A, Seaman MS, Schmidt AG, Chen B, Neuberg D, Bajic G, Harrison SC, Wesemann DR. Tong P, et al. Among authors: mckay lga. Cell. 2021 Sep 16;184(19):4969-4980.e15. doi: 10.1016/j.cell.2021.07.025. Epub 2021 Jul 23. Cell. 2021. PMID: 34332650 Free PMC article.
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain.
Nabel KG, Clark SA, Shankar S, Pan J, Clark LE, Yang P, Coscia A, McKay LGA, Varnum HH, Brusic V, Tolan NV, Zhou G, Desjardins M, Turbett SE, Kanjilal S, Sherman AC, Dighe A, LaRocque RC, Ryan ET, Tylek C, Cohen-Solal JF, Darcy AT, Tavella D, Clabbers A, Fan Y, Griffiths A, Correia IR, Seagal J, Baden LR, Charles RC, Abraham J. Nabel KG, et al. Among authors: mckay lga. Science. 2022 Jan 21;375(6578):eabl6251. doi: 10.1126/science.abl6251. Epub 2022 Jan 21. Science. 2022. PMID: 34855508 Free PMC article.
IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2.
Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK. Nikitin PA, et al. Among authors: mckay lga. Sci Immunol. 2022 Sep 9;7(75):eabl9943. doi: 10.1126/sciimmunol.abl9943. Epub 2022 Sep 9. Sci Immunol. 2022. PMID: 35771946 Free PMC article.
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