Meier H - Search Results

1

A lower X-gate in TASK channels traps inhibitors within the vestibule.

Rödström KEJ, Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, Burgess-Brown NA, Tucker SJ, Müller T, Decher N, Carpenter EP. Rödström KEJ, et al. Among authors: meier h. Nature. 2020 Jun;582(7812):443-447. doi: 10.1038/s41586-020-2250-8. Epub 2020 Apr 29. Nature. 2020. PMID: 32499642

2

Discovery and optimization of 2-aryl oxazolo-pyrimidines as adenosine kinase inhibitors using liquid phase parallel synthesis.

Bauser M, Delapierre G, Hauswald M, Flessner T, D'Urso D, Hermann A, Beyreuther B, De Vry J, Spreyer P, Reissmüller E, Meier H. Bauser M, et al. Among authors: meier h. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1997-2000. doi: 10.1016/j.bmcl.2004.01.082. Bioorg Med Chem Lett. 2004. PMID: 15050645

3

Identification and optimization of substituted 5-aminopyrazoles as potent and selective adenosine A1 receptor antagonists.

Griebenow N, Bärfacker L, Meier H, Schneider D, Teusch N, Lustig K, Kast R, Kolkhof P. Griebenow N, et al. Among authors: meier h. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5891-4. doi: 10.1016/j.bmcl.2010.07.095. Epub 2010 Aug 1. Bioorg Med Chem Lett. 2010. PMID: 20728355

4

Naphthol derivatives as TRPV1 inhibitors for the treatment of urinary incontinence.

Urbahns K, Yura T, Mogi M, Tajimi M, Fujishima H, Masuda T, Yoshida N, Moriwaki T, Lowinger TB, Meier H, Chan F, Madge D, Gupta JB. Urbahns K, et al. Among authors: meier h. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3354-7. doi: 10.1016/j.bmcl.2011.04.013. Epub 2011 Apr 9. Bioorg Med Chem Lett. 2011. PMID: 21531136

5

3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): a novel cannabinoid Cb1/Cb2 receptor partial agonist with antihyperalgesic and antiallodynic effects.

De Vry J, Denzer D, Reissmueller E, Eijckenboom M, Heil M, Meier H, Mauler F. De Vry J, et al. Among authors: meier h. J Pharmacol Exp Ther. 2004 Aug;310(2):620-32. doi: 10.1124/jpet.103.062836. Epub 2004 May 12. J Pharmacol Exp Ther. 2004. PMID: 15140913

6

In silico ADMET traffic lights as a tool for the prioritization of HTS hits.

Lobell M, Hendrix M, Hinzen B, Keldenich J, Meier H, Schmeck C, Schohe-Loop R, Wunberg T, Hillisch A. Lobell M, et al. Among authors: meier h. ChemMedChem. 2006 Nov;1(11):1229-36. doi: 10.1002/cmdc.200600168. ChemMedChem. 2006. PMID: 16991174

7

An approach towards enhancement of a screening library: The Next Generation Library Initiative (NGLI) at Bayer - against all odds?

Follmann M, Briem H, Steinmeyer A, Hillisch A, Schmitt MH, Haning H, Meier H. Follmann M, et al. Among authors: meier h. Drug Discov Today. 2019 Mar;24(3):668-672. doi: 10.1016/j.drudis.2018.12.003. Epub 2018 Dec 15. Drug Discov Today. 2019. PMID: 30562586 Free article. Review.

8

Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits.

Wunberg T, Hendrix M, Hillisch A, Lobell M, Meier H, Schmeck C, Wild H, Hinzen B. Wunberg T, et al. Among authors: meier h. Drug Discov Today. 2006 Feb;11(3-4):175-80. doi: 10.1016/S1359-6446(05)03700-1. Drug Discov Today. 2006. PMID: 16533716 Review.

9

Cognition and Wealth Changes in Mid-to-later Life: A Latent Class Trajectories Approach Using the Health and Retirement Study.

Westrick AC, Esiaka DK, Meier HCS, Rooks RN, Manning M, Tarraf W. Westrick AC, et al. Among authors: meier hcs. J Aging Health. 2024 Feb 14:8982643241232003. doi: 10.1177/08982643241232003. Online ahead of print. J Aging Health. 2024. PMID: 38356174

10

Immune cells are associated with mortality: the Health and Retirement Study.

Seshadri G, Vivek S, Prizment A, Crimmins EM, Klopack ET, Faul J, Guan W, Meier HCS, Thyagarajan B. Seshadri G, et al. Among authors: meier hcs. Front Immunol. 2023 Oct 20;14:1280144. doi: 10.3389/fimmu.2023.1280144. eCollection 2023. Front Immunol. 2023. PMID: 37928548 Free PMC article.

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