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Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers.
Policicchio BB, Xu C, Brocca-Cofano E, Raehtz KD, He T, Ma D, Li H, Sivanandham R, Haret-Richter GS, Dunsmore T, Trichel A, Mellors JW, Hahn BH, Shaw GM, Ribeiro RM, Pandrea I, Apetrei C. Policicchio BB, et al. Among authors: mellors jw. PLoS Pathog. 2016 Sep 15;12(9):e1005879. doi: 10.1371/journal.ppat.1005879. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27632364 Free PMC article.
Nonhuman primate models for HIV cure research.
Apetrei C, Pandrea I, Mellors JW. Apetrei C, et al. Among authors: mellors jw. PLoS Pathog. 2012;8(8):e1002892. doi: 10.1371/journal.ppat.1002892. Epub 2012 Aug 30. PLoS Pathog. 2012. PMID: 22956905 Free PMC article. No abstract available.
Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy.
Kearney MF, Spindler J, Shao W, Yu S, Anderson EM, O'Shea A, Rehm C, Poethke C, Kovacs N, Mellors JW, Coffin JM, Maldarelli F. Kearney MF, et al. Among authors: mellors jw. PLoS Pathog. 2014 Mar 20;10(3):e1004010. doi: 10.1371/journal.ppat.1004010. eCollection 2014 Mar. PLoS Pathog. 2014. PMID: 24651464 Free PMC article.
Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing.
Wei DG, Chiang V, Fyne E, Balakrishnan M, Barnes T, Graupe M, Hesselgesser J, Irrinki A, Murry JP, Stepan G, Stray KM, Tsai A, Yu H, Spindler J, Kearney M, Spina CA, McMahon D, Lalezari J, Sloan D, Mellors J, Geleziunas R, Cihlar T. Wei DG, et al. PLoS Pathog. 2014 Apr 10;10(4):e1004071. doi: 10.1371/journal.ppat.1004071. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24722454 Free PMC article. Clinical Trial.
Simian Immunodeficiency Virus SIVsab Infection of Rhesus Macaques as a Model of Complete Immunological Suppression with Persistent Reservoirs of Replication-Competent Virus: Implications for Cure Research.
Ma D, Xu C, Cillo AR, Policicchio B, Kristoff J, Haret-Richter G, Mellors JW, Pandrea I, Apetrei C. Ma D, et al. Among authors: mellors jw. J Virol. 2015 Jun;89(11):6155-60. doi: 10.1128/JVI.00256-15. Epub 2015 Apr 1. J Virol. 2015. PMID: 25833043 Free PMC article.
465 results