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A single lysine of the two-lysine recognition motif of the D3 domain of receptor-associated protein is sufficient to mediate endocytosis by low-density lipoprotein receptor-related protein.
van den Biggelaar M, Sellink E, Klein Gebbinck JW, Mertens K, Meijer AB. van den Biggelaar M, et al. Among authors: mertens k. Int J Biochem Cell Biol. 2011 Mar;43(3):431-40. doi: 10.1016/j.biocel.2010.11.017. Epub 2010 Dec 7. Int J Biochem Cell Biol. 2011. PMID: 21144910
Functional duplication of ligand-binding domains within low-density lipoprotein receptor-related protein for interaction with receptor associated protein, alpha2-macroglobulin, factor IXa and factor VIII.
Meijer AB, Rohlena J, van der Zwaan C, van Zonneveld AJ, Boertjes RC, Lenting PJ, Mertens K. Meijer AB, et al. Among authors: mertens k. Biochim Biophys Acta. 2007 Jun;1774(6):714-22. doi: 10.1016/j.bbapap.2007.04.003. Epub 2007 Apr 14. Biochim Biophys Acta. 2007. PMID: 17512806
Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.
van den Biggelaar M, Madsen JJ, Faber JH, Zuurveld MG, van der Zwaan C, Olsen OH, Stennicke HR, Mertens K, Meijer AB. van den Biggelaar M, et al. Among authors: mertens k. J Biol Chem. 2015 Jul 3;290(27):16463-76. doi: 10.1074/jbc.M115.650911. Epub 2015 Apr 21. J Biol Chem. 2015. PMID: 25903134 Free PMC article.
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