Mertens K - Search Results

1

Enhanced thrombin sensitivity of a factor VIII-heparin cofactor II hybrid.

Voorberg J, van Stempvoort G, Bos JM, Mertens K, van Mourik JA, Donath MJ. Voorberg J, et al. Among authors: mertens k. J Biol Chem. 1996 Aug 30;271(35):20985-8. doi: 10.1074/jbc.271.35.20985. J Biol Chem. 1996. PMID: 8702860 Free article.

2

Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.

Bovenschen N, Boertjes RC, van Stempvoort G, Voorberg J, Lenting PJ, Meijer AB, Mertens K. Bovenschen N, et al. Among authors: mertens k. J Biol Chem. 2003 Mar 14;278(11):9370-7. doi: 10.1074/jbc.M212053200. Epub 2003 Jan 8. J Biol Chem. 2003. PMID: 12522143 Free article.

3

Characterization of des-(741-1668)-factor VIII, a single-chain factor VIII variant with a fusion site susceptible to proteolysis by thrombin and factor Xa.

Donath MJ, de Laaf RT, Biessels PT, Lenting PJ, van de Loo JW, van Mourik JA, Voorberg J, Mertens K. Donath MJ, et al. Among authors: mertens k. Biochem J. 1995 Nov 15;312 ( Pt 1)(Pt 1):49-55. doi: 10.1042/bj3120049. Biochem J. 1995. PMID: 7492334 Free PMC article.

4

Cleavage at arginine 145 in human blood coagulation factor IX converts the zymogen into a factor VIII binding enzyme.

Lenting PJ, ter Maat H, Clijsters PP, Donath MJ, van Mourik JA, Mertens K. Lenting PJ, et al. Among authors: mertens k. J Biol Chem. 1995 Jun 23;270(25):14884-90. doi: 10.1074/jbc.270.25.14884. J Biol Chem. 1995. PMID: 7797466 Free article.

5

The role of cleavage of the light chain at positions Arg1689 or Arg1721 in subunit interaction and activation of human blood coagulation factor VIII.

Donath MS, Lenting PJ, van Mourik JA, Mertens K. Donath MS, et al. Among authors: mertens k. J Biol Chem. 1995 Feb 24;270(8):3648-55. doi: 10.1074/jbc.270.8.3648. J Biol Chem. 1995. PMID: 7876103 Free article.

6

Identification of a binding site for blood coagulation factor IXa on the light chain of human factor VIII.

Lenting PJ, Donath MJ, van Mourik JA, Mertens K. Lenting PJ, et al. Among authors: mertens k. J Biol Chem. 1994 Mar 11;269(10):7150-5. J Biol Chem. 1994. PMID: 8125924 Free article.

7

Biological activity of recombinant factor VIII variants lacking the central B-domain and the heavy-chain sequence Lys713-Arg740: discordant in vitro and in vivo activity.

Mertens K, Donath MJ, van Leen RW, de Keyzer-Nellen MJ, Verbeet MP, Klaasse Bos JM, Leyte A, van Mourik JA. Mertens K, et al. Br J Haematol. 1993 Sep;85(1):133-42. doi: 10.1111/j.1365-2141.1993.tb08656.x. Br J Haematol. 1993. PMID: 8251380

8

The sequence Glu1811-Lys1818 of human blood coagulation factor VIII comprises a binding site for activated factor IX.

Lenting PJ, van de Loo JW, Donath MJ, van Mourik JA, Mertens K. Lenting PJ, et al. Among authors: mertens k. J Biol Chem. 1996 Jan 26;271(4):1935-40. doi: 10.1074/jbc.271.4.1935. J Biol Chem. 1996. PMID: 8567641 Free article.

In previous studies have shown that the interaction between factor IXa and VIII involves the light chain of factor VIII and that this interaction inhibited by the monoclonal antibody CLB-CAg A against the factor VIII region Gln1778-Asp1840 (Lenting, P.J., Donath, M.J.S.H., van Mo …

In previous studies have shown that the interaction between factor IXa and VIII involves the light chain of factor VIII and that this intera …

9

Kinetics of factor VIII light-chain cleavage by thrombin and factor Xa. A regulatory role of the factor VIII heavy-chain region Lys713-Arg740.

Donath MJ, Lenting PJ, Van Mourik JA, Mertens K. Donath MJ, et al. Among authors: mertens k. Eur J Biochem. 1996 Sep 1;240(2):365-72. doi: 10.1111/j.1432-1033.1996.0365h.x. Eur J Biochem. 1996. PMID: 8841400 Free article.

10

Dissimilar interaction of factor VIII with endothelial cells and lipid vesicles during factor X activation.

Brinkman HJ, Koster P, Mertens K, van Mourik JA. Brinkman HJ, et al. Among authors: mertens k. Biochem J. 1997 May 1;323 ( Pt 3)(Pt 3):735-40. doi: 10.1042/bj3230735. Biochem J. 1997. PMID: 9169607 Free PMC article.

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