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Nicotine activates the chemosensory cation channel TRPA1.
Talavera K, Gees M, Karashima Y, Meseguer VM, Vanoirbeek JA, Damann N, Everaerts W, Benoit M, Janssens A, Vennekens R, Viana F, Nemery B, Nilius B, Voets T. Talavera K, et al. Nat Neurosci. 2009 Oct;12(10):1293-9. doi: 10.1038/nn.2379. Epub 2009 Sep 13. Nat Neurosci. 2009. PMID: 19749751 Free article.
TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.
Meseguer V, Alpizar YA, Luis E, Tajada S, Denlinger B, Fajardo O, Manenschijn JA, Fernández-Peña C, Talavera A, Kichko T, Navia B, Sánchez A, Señarís R, Reeh P, Pérez-García MT, López-López JR, Voets T, Belmonte C, Talavera K, Viana F. Meseguer V, et al. Nat Commun. 2014;5:3125. doi: 10.1038/ncomms4125. Nat Commun. 2014. PMID: 24445575 Free PMC article.
TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells.
Alpizar YA, Boonen B, Sanchez A, Jung C, López-Requena A, Naert R, Steelant B, Luyts K, Plata C, De Vooght V, Vanoirbeek JAJ, Meseguer VM, Voets T, Alvarez JL, Hellings PW, Hoet PHM, Nemery B, Valverde MA, Talavera K. Alpizar YA, et al. Among authors: meseguer vm. Nat Commun. 2017 Oct 20;8(1):1059. doi: 10.1038/s41467-017-01201-3. Nat Commun. 2017. PMID: 29057902 Free PMC article.
TRP Channels as Sensors of Bacterial Endotoxins.
Boonen B, Alpizar YA, Meseguer VM, Talavera K. Boonen B, et al. Among authors: meseguer vm. Toxins (Basel). 2018 Aug 11;10(8):326. doi: 10.3390/toxins10080326. Toxins (Basel). 2018. PMID: 30103489 Free PMC article. Review.
TRPA1 channels: novel targets of 1,4-dihydropyridines.
Fajardo O, Meseguer V, Belmonte C, Viana F. Fajardo O, et al. Among authors: meseguer v. Channels (Austin). 2008 Nov-Dec;2(6):429-38. doi: 10.4161/chan.2.6.7126. Epub 2008 Nov 3. Channels (Austin). 2008. PMID: 18971630
37 results