Metz M - Search Results

1

A quantitative description of the ground-state wave function of Cu(A) by X-ray absorption spectroscopy: comparison to plastocyanin and relevance to electron transfer.

DeBeer George S, Metz M, Szilagyi RK, Wang H, Cramer SP, Lu Y, Tolman WB, Hedman B, Hodgson KO, Solomon EI. DeBeer George S, et al. Among authors: metz m. J Am Chem Soc. 2001 Jun 20;123(24):5757-67. doi: 10.1021/ja004109i. J Am Chem Soc. 2001. PMID: 11403610

2

Dioxygen binding to deoxyhemocyanin: electronic structure and mechanism of the spin-forbidden two-electron reduction of o(2).

Metz M, Solomon EI. Metz M, et al. J Am Chem Soc. 2001 May 30;123(21):4938-50. doi: 10.1021/ja004166b. J Am Chem Soc. 2001. PMID: 11457321

3

Oxygen Binding, Activation, and Reduction to Water by Copper Proteins.

Solomon EI, Chen P, Metz M, Lee SK, Palmer AE. Solomon EI, et al. Among authors: metz m. Angew Chem Int Ed Engl. 2001 Dec 17;40(24):4570-4590. doi: 10.1002/1521-3773(20011217)40:24<4570::aid-anie4570>3.0.co;2-4. Angew Chem Int Ed Engl. 2001. PMID: 12404359

4

Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach.

Metz M, Bourque E, Labrecque J, Danthi SJ, Langille J, Harwig C, Yang W, Darkes MC, Lau G, Santucci Z, Bridger GJ, Schols D, Fricker SP, Skerlj RT. Metz M, et al. J Am Chem Soc. 2011 Oct 19;133(41):16477-85. doi: 10.1021/ja2043722. Epub 2011 Sep 23. J Am Chem Soc. 2011. PMID: 21942640

5

Structural enzymology using X-ray free electron lasers.

Kupitz C, Olmos JL Jr, Holl M, Tremblay L, Pande K, Pandey S, Oberthür D, Hunter M, Liang M, Aquila A, Tenboer J, Calvey G, Katz A, Chen Y, Wiedorn MO, Knoska J, Meents A, Majriani V, Norwood T, Poudyal I, Grant T, Miller MD, Xu W, Tolstikova A, Morgan A, Metz M, Martin-Garcia JM, Zook JD, Roy-Chowdhury S, Coe J, Nagaratnam N, Meza D, Fromme R, Basu S, Frank M, White T, Barty A, Bajt S, Yefanov O, Chapman HN, Zatsepin N, Nelson G, Weierstall U, Spence J, Schwander P, Pollack L, Fromme P, Ourmazd A, Phillips GN Jr, Schmidt M. Kupitz C, et al. Among authors: metz m. Struct Dyn. 2016 Dec 15;4(4):044003. doi: 10.1063/1.4972069. eCollection 2017 Jul. Struct Dyn. 2016. PMID: 28083542 Free PMC article.

6

HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay.

Labrecque J, Metz M, Lau G, Darkes MC, Wong RS, Bogucki D, Carpenter B, Chen G, Li T, Nan S, Schols D, Bridger GJ, Fricker SP, Skerlj RT. Labrecque J, et al. Among authors: metz m. Virology. 2011 May 10;413(2):231-43. doi: 10.1016/j.virol.2011.02.016. Epub 2011 Mar 9. Virology. 2011. PMID: 21388649 Free article.

7

Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication.

Skerlj R, Bridger G, Zhou Y, Bourque E, Langille J, Di Fluri M, Bogucki D, Yang W, Li T, Wang L, Nan S, Baird I, Metz M, Darkes M, Labrecque J, Lau G, Fricker S, Huskens D, Schols D. Skerlj R, et al. Among authors: metz m. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2450-5. doi: 10.1016/j.bmcl.2011.02.058. Epub 2011 Feb 23. Bioorg Med Chem Lett. 2011. PMID: 21398122

8

Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication.

Skerlj R, Bridger G, Zhou Y, Bourque E, McEachern E, Langille J, Harwig C, Veale D, Yang W, Li T, Zhu Y, Bey M, Baird I, Sartori M, Metz M, Mosi R, Nelson K, Bodart V, Wong R, Fricker S, Mac Farland R, Huskens D, Schols D. Skerlj R, et al. Among authors: metz m. Bioorg Med Chem Lett. 2011 Dec 1;21(23):6950-4. doi: 10.1016/j.bmcl.2011.09.133. Epub 2011 Oct 8. Bioorg Med Chem Lett. 2011. PMID: 22033460

9

Chemokine receptor modeling: an interdisciplinary approach to drug design.

Fricker SP, Metz M. Fricker SP, et al. Among authors: metz m. Future Med Chem. 2014 Jan;6(1):91-114. doi: 10.4155/fmc.13.194. Future Med Chem. 2014. PMID: 24358950 Review.

10

Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam small-molecule CXC chemokine receptor 4 inhibitors.

Wong RS, Bodart V, Metz M, Labrecque J, Bridger G, Fricker SP. Wong RS, et al. Among authors: metz m. Mol Pharmacol. 2008 Dec;74(6):1485-95. doi: 10.1124/mol.108.049775. Epub 2008 Sep 2. Mol Pharmacol. 2008. PMID: 18768385

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