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Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging.
Vrisekoop N, van Gent R, de Boer AB, Otto SA, Borleffs JC, Steingrover R, Prins JM, Kuijpers TW, Wolfs TF, Geelen SP, Vulto I, Lansdorp P, Tesselaar K, Borghans JA, Miedema F. Vrisekoop N, et al. Among authors: miedema f. J Immunol. 2008 Jul 15;181(2):1573-81. doi: 10.4049/jimmunol.181.2.1573. J Immunol. 2008. PMID: 18606713
Limited role for the thymus in SIV pathogenesis.
Borghans JA, Hazenberg MD, Miedema F. Borghans JA, et al. Among authors: miedema f. Eur J Immunol. 2005 Jan;35(1):42-5. doi: 10.1002/eji.200425643. Eur J Immunol. 2005. PMID: 15593304 Free article. Review.
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.
den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mögling R, de Boer AB, Willems N, Schrijver EH, Spierenburg G, Gaiser K, Mul E, Otto SA, Ruiter AF, Ackermans MT, Miedema F, Borghans JA, de Boer RJ, Tesselaar K. den Braber I, et al. Among authors: miedema f. Immunity. 2012 Feb 24;36(2):288-97. doi: 10.1016/j.immuni.2012.02.006. Immunity. 2012. PMID: 22365666 Free article.
Functional restoration of human immunodeficiency virus and Epstein-Barr virus-specific CD8(+) T cells during highly active antiretroviral therapy is associated with an increase in CD4(+) T cells.
Kostense S, Otto SA, Knol GJ, Manting EH, Nanlohy NM, Jansen C, Lange JM, van Oers MH, Miedema F, van Baarle D. Kostense S, et al. Among authors: miedema f. Eur J Immunol. 2002 Apr;32(4):1080-9. doi: 10.1002/1521-4141(200204)32:4<1080::AID-IMMU1080>3.0.CO;2-R. Eur J Immunol. 2002. PMID: 11920575 Free article.
321 results