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MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1.
Brundage ME, Tandon P, Eaves DW, Williams JP, Miller SJ, Hennigan RH, Jegga A, Cripe TP, Ratner N. Brundage ME, et al. Among authors: miller sj. Oncogene. 2014 Dec 4;33(49):5626-36. doi: 10.1038/onc.2013.506. Epub 2014 Feb 10. Oncogene. 2014. PMID: 24509877 Free PMC article.
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N. Jessen WJ, et al. Among authors: miller sj. J Clin Invest. 2013 Jan;123(1):340-7. doi: 10.1172/JCI60578. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221341 Free PMC article. Clinical Trial.
Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene.
Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, Lazaro C, Stemmer-Rachamimov A, Page G, Aronow BJ, Ratner N. Miller SJ, et al. EMBO Mol Med. 2009 Jul;1(4):236-48. doi: 10.1002/emmm.200900027. EMBO Mol Med. 2009. PMID: 20049725 Free PMC article.
Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target.
Patel AV, Eaves D, Jessen WJ, Rizvi TA, Ecsedy JA, Qian MG, Aronow BJ, Perentesis JP, Serra E, Cripe TP, Miller SJ, Ratner N. Patel AV, et al. Among authors: miller sj. Clin Cancer Res. 2012 Sep 15;18(18):5020-30. doi: 10.1158/1078-0432.CCR-12-1072. Epub 2012 Jul 18. Clin Cancer Res. 2012. PMID: 22811580 Free PMC article.
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