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Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206.
Ribas A, Camacho LH, Lopez-Berestein G, Pavlov D, Bulanhagui CA, Millham R, Comin-Anduix B, Reuben JM, Seja E, Parker CA, Sharma A, Glaspy JA, Gomez-Navarro J. Ribas A, et al. Among authors: millham r. J Clin Oncol. 2005 Dec 10;23(35):8968-77. doi: 10.1200/JCO.2005.01.109. Epub 2005 Oct 3. J Clin Oncol. 2005. PMID: 16204013 Clinical Trial.
A Phase I Clinical Trial and Independent Patient-Derived Xenograft Study of Combined Targeted Treatment with Dacomitinib and Figitumumab in Advanced Solid Tumors.
Calvo E, Soria JC, Ma WW, Wang T, Bahleda R, Tolcher AW, Gernhardt D, O'Connell J, Millham R, Giri N, Wick MJ, Adjei AA, Hidalgo M. Calvo E, et al. Among authors: millham r. Clin Cancer Res. 2017 Mar 1;23(5):1177-1185. doi: 10.1158/1078-0432.CCR-15-2301. Epub 2016 Oct 12. Clin Cancer Res. 2017. PMID: 27733479 Clinical Trial.
Phase I dose-escalation study of the pan-HER inhibitor, PF299804, in patients with advanced malignant solid tumors.
Jänne PA, Boss DS, Camidge DR, Britten CD, Engelman JA, Garon EB, Guo F, Wong S, Liang J, Letrent S, Millham R, Taylor I, Eckhardt SG, Schellens JH. Jänne PA, et al. Among authors: millham r. Clin Cancer Res. 2011 Mar 1;17(5):1131-9. doi: 10.1158/1078-0432.CCR-10-1220. Epub 2011 Jan 10. Clin Cancer Res. 2011. PMID: 21220471 Free PMC article. Clinical Trial.
First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer.
Shapiro GI, Bell-McGuinn KM, Molina JR, Bendell J, Spicer J, Kwak EL, Pandya SS, Millham R, Borzillo G, Pierce KJ, Han L, Houk BE, Gallo JD, Alsina M, Braña I, Tabernero J. Shapiro GI, et al. Among authors: millham r. Clin Cancer Res. 2015 Apr 15;21(8):1888-95. doi: 10.1158/1078-0432.CCR-14-1306. Epub 2015 Feb 4. Clin Cancer Res. 2015. PMID: 25652454 Free PMC article. Clinical Trial.
Development of inhibitors of the IGF-IR/PI3K/Akt/mTOR pathway.
Hixon ML, Paccagnella L, Millham R, Perez-Olle R, Gualberto A. Hixon ML, et al. Among authors: millham r. Rev Recent Clin Trials. 2010 Sep;5(3):189-208. doi: 10.2174/157488710792007329. Rev Recent Clin Trials. 2010. PMID: 20533896 Review.
14 results