Construction and biological characterization of artificial recombinants between a wild type flavivirus (Kunjin) and a live chimeric flavivirus vaccine (ChimeriVax-JE).
Pugachev KV, Schwaiger J, Brown N, Zhang ZX, Catalan J, Mitchell FS, Ocran SW, Rumyantsev AA, Khromykh AA, Monath TP, Guirakhoo F.
Pugachev KV, et al. Among authors: monath tp.
Vaccine. 2007 Sep 17;25(37-38):6661-71. doi: 10.1016/j.vaccine.2007.07.016. Epub 2007 Jul 27.
Vaccine. 2007.
PMID: 17693000
Although the theoretical concern of genetic recombination has been raised related to the use of live attenuated flavivirus vaccines [Seligman, Gould, Lancet 2004;363:2073-5], it has little foundation [e.g., Monath TP, Kanesa-Thasan N, Guirakhoo F, Pugachev K, Almond …
Although the theoretical concern of genetic recombination has been raised related to the use of live attenuated flavivirus vaccines [Seligma …