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Potently neutralizing and protective human antibodies against SARS-CoV-2.
Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr. Zost SJ, et al. Among authors: mueller bk. Nature. 2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. Epub 2020 Jul 15. Nature. 2020. PMID: 32668443 Free PMC article.
Modeling the complete chemokine-receptor interaction.
Wedemeyer MJ, Mueller BK, Bender BJ, Meiler J, Volkman BF. Wedemeyer MJ, et al. Among authors: mueller bk. Methods Cell Biol. 2019;149:289-314. doi: 10.1016/bs.mcb.2018.09.005. Epub 2018 Nov 1. Methods Cell Biol. 2019. PMID: 30616825 Free PMC article.
Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design.
Schoeder CT, Schmitz S, Adolf-Bryfogle J, Sevy AM, Finn JA, Sauer MF, Bozhanova NG, Mueller BK, Sangha AK, Bonet J, Sheehan JH, Kuenze G, Marlow B, Smith ST, Woods H, Bender BJ, Martina CE, Del Alamo D, Kodali P, Gulsevin A, Schief WR, Correia BE, Crowe JE Jr, Meiler J, Moretti R. Schoeder CT, et al. Among authors: mueller bk. Biochemistry. 2021 Mar 23;60(11):825-846. doi: 10.1021/acs.biochem.0c00912. Epub 2021 Mar 11. Biochemistry. 2021. PMID: 33705117 Free PMC article.
Protocols for Molecular Modeling with Rosetta3 and RosettaScripts.
Bender BJ, Cisneros A 3rd, Duran AM, Finn JA, Fu D, Lokits AD, Mueller BK, Sangha AK, Sauer MF, Sevy AM, Sliwoski G, Sheehan JH, DiMaio F, Meiler J, Moretti R. Bender BJ, et al. Among authors: mueller bk. Biochemistry. 2016 Aug 30;55(34):4748-63. doi: 10.1021/acs.biochem.6b00444. Epub 2016 Aug 16. Biochemistry. 2016. PMID: 27490953 Free PMC article. Review.
Expanding the toolkit for membrane protein modeling in Rosetta.
Koehler Leman J, Mueller BK, Gray JJ. Koehler Leman J, et al. Among authors: mueller bk. Bioinformatics. 2017 Mar 1;33(5):754-756. doi: 10.1093/bioinformatics/btw716. Bioinformatics. 2017. PMID: 28011777 Free PMC article.
The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity.
Wang XF, Vigouroux R, Syonov M, Baglaenko Y, Nikolakopoulou AM, Ringuette D, Rus H, DiStefano PV, Dufour S, Shabanzadeh AP, Lee S, Mueller BK, Charish J, Harada H, Fish JE, Wither J, Wälchli T, Cloutier JF, Zlokovic BV, Carlen PL, Monnier PP. Wang XF, et al. Among authors: mueller bk. Nat Commun. 2024 Feb 3;15(1):1037. doi: 10.1038/s41467-024-45303-1. Nat Commun. 2024. PMID: 38310100 Free PMC article.
Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models.
Huang L, Fung E, Bose S, Popp A, Böser P, Memmott J, Kutskova YA, Miller R, Tarcsa E, Klein C, Veldman GM, Mueller BK, Cui YF. Huang L, et al. Among authors: mueller bk. Neurobiol Dis. 2021 Nov;159:105492. doi: 10.1016/j.nbd.2021.105492. Epub 2021 Aug 31. Neurobiol Dis. 2021. PMID: 34478849 Free article.
Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates.
Jacobson PB, Goody R, Lawrence M, Mueller BK, Zhang X, Hooker BA, Pfleeger K, Ziemann A, Locke C, Barraud Q, Droescher M, Bernhard J, Popp A, Boeser P, Huang L, Mollon J, Mordashova Y, Cui YF, Savaryn JP, Grinnell C, Dreher I, Gold M, Courtine G, Mothe A, Tator CH, Guest JD. Jacobson PB, et al. Among authors: mueller bk. Neurobiol Dis. 2021 Jul;155:105385. doi: 10.1016/j.nbd.2021.105385. Epub 2021 May 12. Neurobiol Dis. 2021. PMID: 33991647 Free article.
54 results