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Melanoma secretion of transforming growth factor-β2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration.
Cosgarea I, McConnell AT, Ewen T, Tang D, Hill DS, Anagnostou M, Elias M, Ellis RA, Murray A, Spender LC, Giglio P, Gagliardi M, Greenwood A, Piacentini M, Inman GJ, Fimia GM, Corazzari M, Armstrong JL, Lovat PE. Cosgarea I, et al. Br J Dermatol. 2022 Apr;186(4):694-704. doi: 10.1111/bjd.20889. Epub 2021 Dec 27. Br J Dermatol. 2022. PMID: 34773645 Free PMC article.
Embryonic zebrafish xenograft assay of human cancer metastasis.
Hill D, Chen L, Snaar-Jagalska E, Chaudhry B. Hill D, et al. F1000Res. 2018 Oct 22;7:1682. doi: 10.12688/f1000research.16659.2. eCollection 2018. F1000Res. 2018. PMID: 30473782 Free PMC article.
We suggest that the embryonic zebrafish xenograft model of human cancer is a tractable laboratory model that can be used to understand cancer biology, and as a direct replacement of mice for the analysis of drugs that target cancer invasion and metastasis....
We suggest that the embryonic zebrafish xenograft model of human cancer is a tractable laboratory model that can be used to understand cance …
Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death.
Armstrong JL, Hill DS, McKee CS, Hernandez-Tiedra S, Lorente M, Lopez-Valero I, Eleni Anagnostou M, Babatunde F, Corazzari M, Redfern CPF, Velasco G, Lovat PE. Armstrong JL, et al. J Invest Dermatol. 2015 Jun;135(6):1629-1637. doi: 10.1038/jid.2015.45. Epub 2015 Feb 10. J Invest Dermatol. 2015. PMID: 25674907 Free article.