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Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains.
Bikker FJ, Ligtenberg AJ, End C, Renner M, Blaich S, Lyer S, Wittig R, van't Hof W, Veerman EC, Nazmi K, de Blieck-Hogervorst JM, Kioschis P, Nieuw Amerongen AV, Poustka A, Mollenhauer J. Bikker FJ, et al. Among authors: nazmi k. J Biol Chem. 2004 Nov 12;279(46):47699-703. doi: 10.1074/jbc.M406095200. Epub 2004 Sep 7. J Biol Chem. 2004. PMID: 15355985 Free article.
CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG.
García-Vallejo JJ, Ilarregui JM, Kalay H, Chamorro S, Koning N, Unger WW, Ambrosini M, Montserrat V, Fernandes RJ, Bruijns SC, van Weering JR, Paauw NJ, O'Toole T, van Horssen J, van der Valk P, Nazmi K, Bolscher JG, Bajramovic J, Dijkstra CD, 't Hart BA, van Kooyk Y. García-Vallejo JJ, et al. Among authors: nazmi k. J Exp Med. 2014 Jun 30;211(7):1465-83. doi: 10.1084/jem.20122192. Epub 2014 Jun 16. J Exp Med. 2014. PMID: 24935259 Free PMC article. Clinical Trial.
The scavenging capacity of DMBT1 is impaired by germline deletions.
Bikker FJ, End C, Ligtenberg AJM, Blaich S, Lyer S, Renner M, Wittig R, Nazmi K, van Nieuw Amerongen A, Poustka A, Veerman ECI, Mollenhauer J. Bikker FJ, et al. Among authors: nazmi k. Immunogenetics. 2017 Jun;69(6):401-407. doi: 10.1007/s00251-017-0982-x. Epub 2017 Mar 31. Immunogenetics. 2017. PMID: 28364129 Free PMC article.
130 results