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TIGIT predominantly regulates the immune response via regulatory T cells.
Kurtulus S, Sakuishi K, Ngiow SF, Joller N, Tan DJ, Teng MW, Smyth MJ, Kuchroo VK, Anderson AC. Kurtulus S, et al. Among authors: ngiow sf. J Clin Invest. 2015 Nov 2;125(11):4053-62. doi: 10.1172/JCI81187. Epub 2015 Sep 28. J Clin Invest. 2015. PMID: 26413872 Free PMC article.
Targeting regulatory T cells in tumor immunotherapy.
Smyth MJ, Ngiow SF, Teng MW. Smyth MJ, et al. Among authors: ngiow sf. Immunol Cell Biol. 2014 Jul;92(6):473-4. doi: 10.1038/icb.2014.33. Epub 2014 Apr 29. Immunol Cell Biol. 2014. PMID: 24777313 No abstract available.
Immunosurveillance and therapy of multiple myeloma are CD226 dependent.
Guillerey C, Ferrari de Andrade L, Vuckovic S, Miles K, Ngiow SF, Yong MC, Teng MW, Colonna M, Ritchie DS, Chesi M, Bergsagel PL, Hill GR, Smyth MJ, Martinet L. Guillerey C, et al. Among authors: ngiow sf. J Clin Invest. 2015 May;125(5):2077-89. doi: 10.1172/JCI77181. Epub 2015 Apr 20. J Clin Invest. 2015. PMID: 25893601 Free PMC article.
Prospects for TIM3-Targeted Antitumor Immunotherapy.
Ngiow SF, Teng MW, Smyth MJ. Ngiow SF, et al. Cancer Res. 2011 Nov 1;71(21):6567-71. doi: 10.1158/0008-5472.CAN-11-1487. Epub 2011 Oct 18. Cancer Res. 2011. PMID: 22009533 Review.
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. Knight DA, et al. Among authors: ngiow sf. J Clin Invest. 2013 Mar;123(3):1371-81. doi: 10.1172/JCI66236. Epub 2013 Feb 1. J Clin Invest. 2013. PMID: 23454771 Free PMC article.
Classifying Cancers Based on T-cell Infiltration and PD-L1.
Teng MW, Ngiow SF, Ribas A, Smyth MJ. Teng MW, et al. Among authors: ngiow sf. Cancer Res. 2015 Jun 1;75(11):2139-45. doi: 10.1158/0008-5472.CAN-15-0255. Cancer Res. 2015. PMID: 25977340 Free PMC article. Review.
56 results