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Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids.
Llewellyn SV, Kermanizadeh A, Ude V, Jacobsen NR, Conway GE, Shah UK, Niemeijer M, Moné MJ, van de Water B, Roy S, Moritz W, Stone V, Jenkins GJS, Doak SH. Llewellyn SV, et al. Among authors: niemeijer m. Toxicol In Vitro. 2022 Dec;85:105473. doi: 10.1016/j.tiv.2022.105473. Epub 2022 Sep 13. Toxicol In Vitro. 2022. PMID: 36108805 Free article.
Model-based translation of DNA damage signaling dynamics across cell types.
Heldring MM, Wijaya LS, Niemeijer M, Yang H, Lakhal T, Le Dévédec SE, van de Water B, Beltman JB. Heldring MM, et al. Among authors: niemeijer m. PLoS Comput Biol. 2022 Jul 8;18(7):e1010264. doi: 10.1371/journal.pcbi.1010264. eCollection 2022 Jul. PLoS Comput Biol. 2022. PMID: 35802572 Free PMC article.
Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids.
Shi S, Verstegen MMA, Roest HP, Ardisasmita AI, Cao W, Roos FJM, de Ruiter PE, Niemeijer M, Pan Q, IJzermans JNM, van der Laan LJW. Shi S, et al. Among authors: niemeijer m. Cell Mol Gastroenterol Hepatol. 2022;13(2):541-564. doi: 10.1016/j.jcmgh.2021.10.009. Epub 2021 Oct 23. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34700031 Free PMC article.
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment.
Callegaro G, Kunnen SJ, Trairatphisan P, Grosdidier S, Niemeijer M, den Hollander W, Guney E, Piñero Gonzalez J, Furlong L, Webster YW, Saez-Rodriguez J, Sutherland JJ, Mollon J, Stevens JL, van de Water B. Callegaro G, et al. Among authors: niemeijer m. Arch Toxicol. 2021 Dec;95(12):3745-3775. doi: 10.1007/s00204-021-03141-w. Epub 2021 Oct 9. Arch Toxicol. 2021. PMID: 34626214 Free PMC article.
100 results