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MAGraine: Magnesium compared to conventional therapy for treatment of migraines.
Kandil M, Jaber S, Desai D, Nuñez Cruz S, Lomotan N, Ahmad U, Cirone M, Burkins J, McDowell M. Kandil M, et al. Among authors: nunez cruz s. Am J Emerg Med. 2021 Jan;39:28-33. doi: 10.1016/j.ajem.2020.09.033. Epub 2020 Sep 14. Am J Emerg Med. 2021. PMID: 33041146 Free PMC article. Clinical Trial.
Chimeric kinase ALK induces expression of NAMPT and selectively depends on this metabolic enzyme to sustain its own oncogenic function.
Zhang Q, Basappa J, Wang HY, Nunez-Cruz S, Lobello C, Wang S, Liu X, Chekol S, Guo L, Ziober A, Nejati R, Shestov A, Feldman M, Glickson JD, Turner SD, Blair IA, Van Dang C, Wasik MA. Zhang Q, et al. Among authors: nunez cruz s. Leukemia. 2023 Dec;37(12):2436-2447. doi: 10.1038/s41375-023-02038-0. Epub 2023 Sep 29. Leukemia. 2023. PMID: 37773266
CD38 as a pan-hematologic target for chimeric antigen receptor T cells.
Glisovic-Aplenc T, Diorio C, Chukinas JA, Veliz K, Shestova O, Shen F, Nunez-Cruz S, Vincent TL, Miao F, Milone MC, June CH, Teachey DT, Tasian SK, Aplenc R, Gill S. Glisovic-Aplenc T, et al. Among authors: nunez cruz s. Blood Adv. 2023 Aug 22;7(16):4418-4430. doi: 10.1182/bloodadvances.2022007059. Blood Adv. 2023. PMID: 37171449 Free PMC article.
Induction of Transcriptional Inhibitor HES1 and the Related Repression of Tumor-Suppressor TXNIP Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase NPM-ALK.
Zhang Q, Wang HY, Nayak A, Nunez-Cruz S, Slupianek A, Liu X, Basappa J, Fan JS, Chekol S, Nejati R, Bogusz AM, Turner SD, Swaminathan K, Wasik MA. Zhang Q, et al. Among authors: nunez cruz s. Am J Pathol. 2022 Aug;192(8):1186-1198. doi: 10.1016/j.ajpath.2022.05.005. Epub 2022 May 28. Am J Pathol. 2022. PMID: 35640677 Free PMC article.
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
Zhang H, Yu P, Tomar VS, Chen X, Atherton MJ, Lu Z, Zhang HG, Li S, Ortiz A, Gui J, Leu NA, Yan F, Blanco A, Meyer-Ficca ML, Meyer RG, Beiting DP, Li J, Nunez-Cruz S, O'Connor RS, Johnson LR, Minn AJ, George SS, Koumenis C, Diehl JA, Milone MC, Zheng H, Fuchs SY. Zhang H, et al. Among authors: nunez cruz s. Nat Cancer. 2022 Jul;3(7):808-820. doi: 10.1038/s43018-022-00383-0. Epub 2022 May 30. Nat Cancer. 2022. PMID: 35637402 Free PMC article.
Rapid manufacturing of non-activated potent CAR T cells.
Ghassemi S, Durgin JS, Nunez-Cruz S, Patel J, Leferovich J, Pinzone M, Shen F, Cummins KD, Plesa G, Cantu VA, Reddy S, Bushman FD, Gill SI, O'Doherty U, O'Connor RS, Milone MC. Ghassemi S, et al. Among authors: nunez cruz s. Nat Biomed Eng. 2022 Feb;6(2):118-128. doi: 10.1038/s41551-021-00842-6. Epub 2022 Feb 21. Nat Biomed Eng. 2022. PMID: 35190680 Free PMC article.
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