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Muscle-specific Pparg deletion causes insulin resistance.
Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J. Hevener AL, et al. Among authors: olson p. Nat Med. 2003 Dec;9(12):1491-7. doi: 10.1038/nm956. Epub 2003 Nov 16. Nat Med. 2003. PMID: 14625542
PPAR gamma signaling exacerbates mammary gland tumor development.
Saez E, Rosenfeld J, Livolsi A, Olson P, Lombardo E, Nelson M, Banayo E, Cardiff RD, Izpisua-Belmonte JC, Evans RM. Saez E, et al. Among authors: olson p. Genes Dev. 2004 Mar 1;18(5):528-40. doi: 10.1101/gad.1167804. Genes Dev. 2004. PMID: 15037548 Free PMC article.
PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. Barish GD, et al. Among authors: olson p. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4271-6. doi: 10.1073/pnas.0711875105. Epub 2008 Mar 12. Proc Natl Acad Sci U S A. 2008. PMID: 18337509 Free PMC article.
PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization.
Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, Evans RM. Sugii S, et al. Among authors: olson p. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22504-9. doi: 10.1073/pnas.0912487106. Epub 2009 Dec 16. Proc Natl Acad Sci U S A. 2009. PMID: 20018750 Free PMC article.
PPARdelta regulates glucose metabolism and insulin sensitivity.
Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM. Lee CH, et al. Among authors: olson p. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3444-9. doi: 10.1073/pnas.0511253103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492734 Free PMC article.
498 results