Opresko P - Search Results

1

Association of TERT promoter mutations with telomerase expression in melanoma.

Lee S, Opresko P, Pappo A, Kirkwood JM, Bahrami A. Lee S, et al. Among authors: opresko p. Pigment Cell Melanoma Res. 2016 May;29(3):391-3. doi: 10.1111/pcmr.12471. Pigment Cell Melanoma Res. 2016. PMID: 26928778 Free PMC article. No abstract available.

2

The mutator form of polymerase beta with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors.

Opresko PL, Sweasy JB, Eckert KA. Opresko PL, et al. Biochemistry. 1998 Feb 24;37(8):2111-9. doi: 10.1021/bi9722711. Biochemistry. 1998. PMID: 9485358

3

Molecular mechanisms by which oxidative DNA damage promotes telomerase activity.

Lee HT, Bose A, Lee CY, Opresko PL, Myong S. Lee HT, et al. Nucleic Acids Res. 2017 Nov 16;45(20):11752-11765. doi: 10.1093/nar/gkx789. Nucleic Acids Res. 2017. PMID: 28981887 Free PMC article.

4

Mechanisms of nucleotide selection by telomerase.

Schaich MA, Sanford SL, Welfer GA, Johnson SA, Khoang TH, Opresko PL, Freudenthal BD. Schaich MA, et al. Elife. 2020 Jun 5;9:e55438. doi: 10.7554/eLife.55438. Elife. 2020. PMID: 32501800 Free PMC article.

5

Position-Dependent Effect of Guanine Base Damage and Mutations on Telomeric G-Quadruplex and Telomerase Extension.

Lee HT, Sanford S, Paul T, Choe J, Bose A, Opresko PL, Myong S. Lee HT, et al. Biochemistry. 2020 Jul 21;59(28):2627-2639. doi: 10.1021/acs.biochem.0c00434. Epub 2020 Jun 29. Biochemistry. 2020. PMID: 32578995 Free PMC article.

6

How DNA damage and non-canonical nucleotides alter the telomerase catalytic cycle.

Sanford SL, Welfer GA, Freudenthal BD, Opresko PL. Sanford SL, et al. DNA Repair (Amst). 2021 Nov;107:103198. doi: 10.1016/j.dnarep.2021.103198. Epub 2021 Jul 31. DNA Repair (Amst). 2021. PMID: 34371388 Free PMC article.

7

UV light-induced dual promoter mutations dismantle the telomeric guardrails in melanoma.

Sanford SL, Opresko PL. Sanford SL, et al. Among authors: opresko pl. DNA Repair (Amst). 2023 Feb;122:103446. doi: 10.1016/j.dnarep.2022.103446. Epub 2022 Dec 30. DNA Repair (Amst). 2023. PMID: 36603239 Free PMC article. Review.

8

Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants.

Welfer GA, Borin VA, Cortez LM, Opresko PL, Agarwal PK, Freudenthal BD. Welfer GA, et al. Among authors: opresko pl. Genes (Basel). 2023 Jan 21;14(2):281. doi: 10.3390/genes14020281. Genes (Basel). 2023. PMID: 36833208 Free PMC article.

9

Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences.

Damerla RR, Knickelbein KE, Strutt S, Liu FJ, Wang H, Opresko PL. Damerla RR, et al. Cell Cycle. 2012 Aug 15;11(16):3036-44. doi: 10.4161/cc.21399. Epub 2012 Aug 8. Cell Cycle. 2012. PMID: 22871734 Free PMC article.

10

Telomere-associated aging disorders.

Opresko PL, Shay JW. Opresko PL, et al. Ageing Res Rev. 2017 Jan;33:52-66. doi: 10.1016/j.arr.2016.05.009. Epub 2016 May 20. Ageing Res Rev. 2017. PMID: 27215853 Free PMC article. Review.

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