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Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.
Koenis DS, Medzikovic L, Vos M, Beldman TJ, van Loenen PB, van Tiel CM, Hamers AAJ, Otermin Rubio I, de Waard V, de Vries CJM. Koenis DS, et al. Among authors: otermin rubio i. J Biol Chem. 2018 Sep 28;293(39):15070-15083. doi: 10.1074/jbc.RA118.002720. Epub 2018 Aug 15. J Biol Chem. 2018. PMID: 30111591 Free PMC article.