Pöhlmann S - Search Results

1

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S, Schiergens TS, Herrler G, Wu NH, Nitsche A, Müller MA, Drosten C, Pöhlmann S. Hoffmann M, et al. Among authors: pohlmann s. Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5. Cell. 2020. PMID: 32142651 Free PMC article.

2

Cellular entry of the SARS coronavirus.

Hofmann H, Pöhlmann S. Hofmann H, et al. Among authors: pohlmann s. Trends Microbiol. 2004 Oct;12(10):466-72. doi: 10.1016/j.tim.2004.08.008. Trends Microbiol. 2004. PMID: 15381196 Free PMC article. Review.

3

Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide.

Münch J, Ständker L, Adermann K, Schulz A, Schindler M, Chinnadurai R, Pöhlmann S, Chaipan C, Biet T, Peters T, Meyer B, Wilhelm D, Lu H, Jing W, Jiang S, Forssmann WG, Kirchhoff F. Münch J, et al. Among authors: pohlmann s. Cell. 2007 Apr 20;129(2):263-75. doi: 10.1016/j.cell.2007.02.042. Cell. 2007. PMID: 17448989 Free article.

4

Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.

Glowacka I, Bertram S, Herzog P, Pfefferle S, Steffen I, Muench MO, Simmons G, Hofmann H, Kuri T, Weber F, Eichler J, Drosten C, Pöhlmann S. Glowacka I, et al. Among authors: pohlmann s. J Virol. 2010 Jan;84(2):1198-205. doi: 10.1128/JVI.01248-09. Epub 2009 Oct 28. J Virol. 2010. PMID: 19864379 Free PMC article.

5

A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms.

Zhou Y, Lu K, Pfefferle S, Bertram S, Glowacka I, Drosten C, Pöhlmann S, Simmons G. Zhou Y, et al. Among authors: pohlmann s. J Virol. 2010 Sep;84(17):8753-64. doi: 10.1128/JVI.00554-10. Epub 2010 Jun 23. J Virol. 2010. PMID: 20573835 Free PMC article.

6

Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response.

Glowacka I, Bertram S, Müller MA, Allen P, Soilleux E, Pfefferle S, Steffen I, Tsegaye TS, He Y, Gnirss K, Niemeyer D, Schneider H, Drosten C, Pöhlmann S. Glowacka I, et al. Among authors: pohlmann s. J Virol. 2011 May;85(9):4122-34. doi: 10.1128/JVI.02232-10. Epub 2011 Feb 16. J Virol. 2011. PMID: 21325420 Free PMC article.

7

Comparative analysis of Ebola virus glycoprotein interactions with human and bat cells.

Kühl A, Hoffmann M, Müller MA, Munster VJ, Gnirss K, Kiene M, Tsegaye TS, Behrens G, Herrler G, Feldmann H, Drosten C, Pöhlmann S. Kühl A, et al. Among authors: pohlmann s. J Infect Dis. 2011 Nov;204 Suppl 3(Suppl 3):S840-9. doi: 10.1093/infdis/jir306. J Infect Dis. 2011. PMID: 21987760 Free PMC article.

8

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease.

Bertram S, Glowacka I, Müller MA, Lavender H, Gnirss K, Nehlmeier I, Niemeyer D, He Y, Simmons G, Drosten C, Soilleux EJ, Jahn O, Steffen I, Pöhlmann S. Bertram S, et al. Among authors: pohlmann s. J Virol. 2011 Dec;85(24):13363-72. doi: 10.1128/JVI.05300-11. Epub 2011 Oct 12. J Virol. 2011. PMID: 21994442 Free PMC article.

9

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.

Pfefferle S, Schöpf J, Kögl M, Friedel CC, Müller MA, Carbajo-Lozoya J, Stellberger T, von Dall'Armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, Züst R, Pumpor K, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel HJ, Schwegmann-Wessels C, Pöhlmann S, Haas J, Drosten C, von Brunn A. Pfefferle S, et al. Among authors: pohlmann s. PLoS Pathog. 2011 Oct;7(10):e1002331. doi: 10.1371/journal.ppat.1002331. Epub 2011 Oct 27. PLoS Pathog. 2011. PMID: 22046132 Free PMC article.

10

Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression.

Gnirss K, Kühl A, Karsten C, Glowacka I, Bertram S, Kaup F, Hofmann H, Pöhlmann S. Gnirss K, et al. Among authors: pohlmann s. Virology. 2012 Mar 1;424(1):3-10. doi: 10.1016/j.virol.2011.11.031. Epub 2012 Jan 4. Virology. 2012. PMID: 22222211 Free PMC article.

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