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2015 2
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure.
Beltra JC, Abdel-Hakeem MS, Manne S, Zhang Z, Huang H, Kurachi M, Su L, Picton L, Ngiow SF, Muroyama Y, Casella V, Huang YJ, Giles JR, Mathew D, Belman J, Klapholz M, Decaluwe H, Huang AC, Berger SL, Garcia KC, Wherry EJ. Beltra JC, et al. Immunity. 2023 Dec 12;56(12):2699-2718.e11. doi: 10.1016/j.immuni.2023.11.005. Immunity. 2023. PMID: 38091951
Regulatory T cells in dominant immunologic tolerance.
Georgiev P, Benamar M, Han S, Haigis MC, Sharpe AH, Chatila TA. Georgiev P, et al. J Allergy Clin Immunol. 2024 Jan;153(1):28-41. doi: 10.1016/j.jaci.2023.09.025. Epub 2023 Sep 29. J Allergy Clin Immunol. 2024. PMID: 37778472 Review.
LAG-3 as the third checkpoint inhibitor.
Aggarwal V, Workman CJ, Vignali DAA. Aggarwal V, et al. Nat Immunol. 2023 Sep;24(9):1415-1422. doi: 10.1038/s41590-023-01569-z. Epub 2023 Jul 24. Nat Immunol. 2023. PMID: 37488429 Review.
The enteric nervous system relays psychological stress to intestinal inflammation.
Schneider KM, Blank N, Alvarez Y, Thum K, Lundgren P, Litichevskiy L, Sleeman M, Bahnsen K, Kim J, Kardo S, Patel S, Dohnalová L, Uhr GT, Descamps HC, Kircher S, McSween AM, Ardabili AR, Nemec KM, Jimenez MT, Glotfelty LG, Eisenberg JD, Furth EE, Henao-Mejia J, Bennett FC, Pierik MJ, Romberg-Camps M, Mujagic Z, Prinz M, Schneider CV, Wherry EJ, Bewtra M, Heuckeroth RO, Levy M, Thaiss CA. Schneider KM, et al. Cell. 2023 Jun 22;186(13):2823-2838.e20. doi: 10.1016/j.cell.2023.05.001. Epub 2023 May 25. Cell. 2023. PMID: 37236193
110 results