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Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.
Rice AD, Adams MM, Wallace G, Burrage AM, Lindsey SF, Smith AJ, Swetnam D, Manning BR, Gray SA, Lampert B, Foster S, Lanier R, Robertson A, Painter G, Moyer RW. Rice AD, et al. Among authors: painter g. Viruses. 2011 Jan;3(1):47-62. doi: 10.3390/v3010047. Viruses. 2011. PMID: 21373379 Free PMC article. Review.
Development of CMX001 for the Treatment of Poxvirus Infections.
Lanier R, Trost L, Tippin T, Lampert B, Robertson A, Foster S, Rose M, Painter W, O'Mahony R, Almond M, Painter G. Lanier R, et al. Among authors: painter w, painter g. Viruses. 2010 Dec;2(12):2740-2762. doi: 10.3390/v2122740. Viruses. 2010. PMID: 21499452 Free PMC article.
First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses.
Painter W, Robertson A, Trost LC, Godkin S, Lampert B, Painter G. Painter W, et al. Among authors: painter g. Antimicrob Agents Chemother. 2012 May;56(5):2726-34. doi: 10.1128/AAC.05983-11. Epub 2012 Mar 5. Antimicrob Agents Chemother. 2012. PMID: 22391537 Free PMC article. Clinical Trial.
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox.
Parker S, Chen NG, Foster S, Hartzler H, Hembrador E, Hruby D, Jordan R, Lanier R, Painter G, Painter W, Sagartz JE, Schriewer J, Mark Buller R. Parker S, et al. Among authors: painter g, painter w. Antiviral Res. 2012 Apr;94(1):44-53. doi: 10.1016/j.antiviral.2012.02.005. Epub 2012 Feb 18. Antiviral Res. 2012. PMID: 22381921 Free PMC article.
Co-administration of the broad-spectrum antiviral, brincidofovir (CMX001), with smallpox vaccine does not compromise vaccine protection in mice challenged with ectromelia virus.
Parker S, Crump R, Foster S, Hartzler H, Hembrador E, Lanier ER, Painter G, Schriewer J, Trost LC, Buller RM. Parker S, et al. Among authors: painter g. Antiviral Res. 2014 Nov;111:42-52. doi: 10.1016/j.antiviral.2014.08.003. Epub 2014 Aug 13. Antiviral Res. 2014. PMID: 25128688 Free PMC article.
218 results